ZRdb KZFP & Repeats
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LTR_HERVK22

  • Name
    HERVK22
  • Repbase
    HERVK22I
  • Type
    LTR
  • Emergence
    43.0 Mya
  • Dfam Id
    DF0000194
Description :

The long terminal repeat associated with this ERVK is LTR22C0, but thereare several variant LTR22 subfamilies. These produce 6 bp TSDs.Features: Methionine PBS (~3-20), gag (~138-1692), protease(~1533-2327), pol (~2270-5002), env (~4779-end), and polypyrimidinetract (~6810-6823) Two frequently observed deletions: (a) gag-proteaseregion (~768-2303 and (b) env region (~5314-6641).
Consensus sequence The consensus sequences obtained from Dfam are derived from the seed alignment using a specialized caller. :
ggtggtgccccgcgtgaggaacgctgcaaacggatcgcgacggaaccctcgaaaacgaaggtgaagagaactgcgcagtcagtgagtnnncagtaagtcattggtgcccgctcgggatttccaagttcgaggggaattgttcaggctagggtttcatcatgggacaacagttatcagctcaacagaaacagtatataaaagtattgaaacagctgcttaaagctagcggagcctcggtttcgcaggctcaattaagggacctaatgcaaactgttgtttcccataacccatggttcccggaagaaggcacgctagacgtagagctctgggaacaagtggggagaaatcttaaacaacatcatgcgcaagggcaacgggtcccagtaacatctttaacgttatgggccttagttagggcngctttggccccgctctacacagaagagcctaaaaagggaagggaggaggaaccgtcacctaccttaccgcctcctcctccctcagccccgccatcaccgggcaaaaataacaaagaggaaacggaggttttgcctgagccccctcctccaataaattggaaaaaagacaagggatacgctacagctatgggaccctgtcttaggcaagcggcattagaaggggagctcttagcctgcccggtaatgcaagatcgacaaggcaatcaggtatatgaacccatttcttttaacgcttataaagagataagaaaaagcattagagaaaacggagccgctagcccatttacgaaaggattaattgaggccatagcagacaacttccgtatgaccccatgggactggtcagtgctagctaaaacaactttagagnccagtcaatacctcctctggagggcagaatatgatgagttgtgcgaacaacaagccaaccagaatcaattggccgggcaagacataacagctgctatgctccaggggaggggtccccatgccgatgtacaacaactaaattttgatccccaggcctatgcacaagtgtctttgtgcgctctcagggcttgggaccgaattcccgaaagcggagttcaacagggatcttttataaatgttcgacaagggcctcaggagccatttgttgaatttatcaatcggttaacccaggcaattaagagacaaattagtcacgcccaggccgctgatatcttattgttgcaattggcttatgaaaatgctaatgtngactgccagcaagcaatgcaggcaatcagaggaaaggcagccacagtcggggaacttatacgagcatgtcaactggtggggactgaaacacacaaagccaaaatattggctatggcattaaggcctcctaaagtgaaaagggagagaaacccaaattgttttctatgcggagagccaggtcatatgaagagggaatgccccaatagtagagaccaaggtaactcaggaaaagaacccccttctatatgcccccgatgtaaaaaggggaaacattgggcaaatcaatgcaggtccaaatttgataaaaacggcaaccccataagtaaccaggcgggaaacttcatgaggggccggccccaggccccgctccaaactggggcaatgccagcggctttcctcggtcagatggaaagcccacagtcctctctctcagagcagccaccactgggagcgcaggactggacttactctgccccaacgaattagtgctaaaagaaggagaagaccctaaaagggttgcaaccgggatctggggcccactgcctccgggaacagtgggattagtcctagggcgatcaagcctatccagtaaaggaattaatgtgctcaccggggtaattgatagtgattatcaaggtgagatattagttatgatggaatgtaaaggtctgcatattcttccccctggatcaaagatagctcagttactacttttaccatactgggtccccaatgcccagggaaaggaaaggggaaagggaagttttggaagcacgggagccacaggagtatattggaaccaattaatcactgatcagagacccatgattaccttaaaaattggaaataaaaattttactggcttattggacacaggggcggacatttcgatcattagtgatcaaaactggccagaaacttggccttgggtcactcagaaacaaaaaattgtcggcatcggggaagcgcacacagccaagcagagcacgcgccccctaacatgttgcgattcggagggaagaaaggcagttatacaacctctaatcatgcccatccctgttaatctttggggacgggacctattagcccaatgnggggggtcactctgcagacccctttctaataatggccactgttattattcctcccctacccctgacgtggctctctcaagatccaatttgggtagaacagtggcctttaaagggagagaaattacaaagagcccatgaattagttgaggagcaattaaaagccggccatatagaaccatcaaacagcccttggaattcgcccattttcgtcattcccaaaaagtctggtaaatggagacttttgcatgacttacgtgctatcaatgctaatttgcaacctatggggccccttcaacaggggctcccttcccccgcggcgattcctcgagattggcctatagtcgttattgacttaaaagactgcttttatactattccccttgcagaacaggacagagaaaaatttgcgtttacaataccagctatcaataatgaaaggccagctcgccgatttcattggaaagtgcttcctcaaggaatgctgaacagtcctaccatgtgtcagtatcatgtaaatcaggctttgctccccagtagaaaagaatttcctaattgcaagattattcattttatggatgatattttactagcagccccaacggagccagtacttttaagtttatatgcctctgtcgtaaagaatacacagttaagaggtttaatcatagcacctgaaaaagtacagatgtcctctccttggaaatatcttgggtacatactaacttcccggtcagtaagacctcaaaaggttaaattaaatactagcaacttacacaccttaaatgattatcagaaattactgggcgatattaactggcttcgccccaccttgggcataactactgataagttacaaaacctgttttctatcctaaagggcaatgcagccctagactctcccaggtatttaacccctgcagcaaaaagggaaattgaggaaatagagcaagctatttctcagaggcaactagatcgcatagacccacgatattcagttcaattgtttgtttttcccactaaacactccccnacaggattaataggacagatggccccagggctgcgcttcctagaatgggttttttcgctcacataccgggactaaaacactatctccctatatccagctagttagtaaagtcatctattcaggccgcagacgatgcaatcagttgctaggttatgaccctgatgtcatcagaattcctttaagtaaaaagcaattcgaagcagtattgcccttatctctagacctgcaaatagcactctctgattacgcaggccatatagagcatgcccttcctgctgacaaactacttcagttcttatctcgtactcctgtagttttgcctacaaaagtagttcactcccccatacctaacgctttaacgctgtttactgatggctctggtaaanatggaaaagcggctgtctggtggagaccgcataattccctcactcgntctggatttactagcactcagagagctgaggttggagccctaatattggccctggaaactttttccgctcagcccatcaatattgttagtgactctgcttactctgtttatttattgcagaaccttgagacagccctcattaagtccactctngagcccaccctgtgtgcnctttttcttcgacttcagcaattgctagatcaacgtacacatcctatttttatcacacacattcgagcccacagctcactgcctggcccactggcttatggcaatgatcaagcagacctgcaggttatgacgtcactgcttgaccaagccacccaatcgcatcaatttttccaccaaaattggagaaacttatctaaacaatttcaacttacccagagactagctaaacaaattatcctgcaatgcccagattgccagctcacaggcacgtcccctccttcaacaggtgttaaccctagaggactagaacctaatcagttatggcaaacagatgttacacacgtccctgaatttggaaaactaagatatgtacatgtatccgttgataccaattctcacctaattagcgcncatgctcttcctggagagtccacccgatatgtcattaaacatcttcttttaacttttgcgtttatggggcggcccacaaaaattaaaactgataatggtccggcttatgccagctcacaatttcaacaattttgtcacacgtggaacatccaacattccacaggcatcccgtataacccccaaggacaggccatagtagaacgtgcccactccacccttaaaaatatgctcagaaaacaaaaaagggggaatatgagtaaggaccctgcaacactattggcacaagccttatttacccttaattttttaaatttagatgataaatttcaatcagctgtagaaaagcactttgctaaaacctctcaagacataaaacctgcagttttatggaaagatgtaaacagtaatgtatggtgtggtccaaatgaattgctaacgtggggaagaggatatgcttgtgttcacaccccctcaggtcctctttggattccagcacgacgcatcaaaccataccatggcgtggctaggacccaacccggtaccagaaatgaaggaaatgaccctgcaggacccgcagccccggacgatgcggcttcctcggacgacacaagccccggacattacctgggggatgctgaagaagacaactcaggaggctgagcgaatcctgctccggacacagacaccattcactccagataatttgttccttgctatgctttctgttgtacattgcaactcncgtagggtattgatcctttttatnctctcgctttgcctgcaacccgtacctgctacactctattgggcccatctcttagatccgcctttcttccgccctgttacctgggcagacacccccttcccagcctctaataacgtaactgcttggctaggagggatngacttacccccagtggggtccctcantaatggcacacattggactaaggtgccaggtaacactacatatcactccactatcctcccactgtgtgtaagttataaaagttctaacccttactgtgtacctgcccaaacacaattatggctacatcatggcaaaggaaatgccttaacantcttagctgcaggtagcctcaaaccgggcaatgcaatcaatgccactttcccaaacattccttcctgtgctaaagaacaaagccgggaaagtaatggattccactttagctgggaggtctgtcacgggggacaagcccgtagcctccagttaggcaattataacatcttagactggagcccccacggccatttgcagggcggccntactgatgtccncgtccatcgtggcatcaatcacagtttcgtagccacgtcccgttcccctatgatttgggccgatggggggatgggatatcccagaccccaagtaaagtccatgccaccccaagacactttatggcgcctgggacatcttagcacctcccttaacacctggcatgggacatatcataattccagtnacaactatactatgacctttattcataatcacactgatcagtgcctgatttgcactacccatccatatgttttccttatgggaaccaatatttccattacaccccaaaactccacgtttgtgacccgggtgcagggacaggcttggttcgcctcatgtatcactaattacaatatatctaatttaaatattactagtgtcatggtattaaggagacaatctgaggcattcctaccagtcaatttgacacgcgattggcaaggttcctctgcccttgccaccttagaacgtgccctgtcccaggtcagacacaaaagattcatagttacacttatagcctttatagtctcagccatagtcatcctagcaactgctagtgttgctgtggcatctattactgaatcagtacaaacagctgcctttgtagataatttggccagaaatgtgtctaatgaacttctcttacagcagggtatagatcaaaagattcttgcacgtctgcaagccctcgaggctgccttggaatatgtgggggagcgacaagatgcactggcattccgacagcaattaaactgcgactgggagcataagcatatctgtgtcacttctctaccatggaatcaatcaatacatagttgggatgaggtgaaacaacacctctggggaacctttcatgacaatttaacagcagacgtaaagcaacttaaaactaaaattctagaatccctnnacgccatagatctacacgcccaacaaacagccatatggaagggtgtgcgagatcatctctcctggatagacccccgctcctgggggtcactccttgattggaaaagaatgttgctaattatactcatgtttgtcttatgttatttactaattctaggatgcaaagccggaatacgagcagtgaccgccgcgcctgacaaacctgttgctgcacacatctgtactcttcaatcaacaaaacctgatgcaaaaaacagaaaagggggaga
Repeats structure For certain families, there exists a curated collection of TE-derived proteins, which constitutes a non-redundant set. As a results, several families may lack an associated coding sequences directly linked to them. The annotation for these families is obtained from Dfam. :
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Peak overlapping A ChIP-seq peak of KZFPs that intersects with a certain repeats sequence on the genome. :
# KZFP name Record number KZFP age(Mya) Time correlation with Repeats
1 ZNF419 95 28.9 Moderately correlated
2 ZNF382 46 99.0 Weakly correlated
3 ZNF28 31 28.9 Moderately correlated
4 ZNF766 23 43.0 Highly correlated
5 ZNF589 17 28.9 Moderately correlated
6 ZNF317 15 99.0 Weakly correlated
7 ZNF394 14 99.0 Weakly correlated
8 ZNF2 13 99.0 Weakly correlated
9 ZNF175 12 94.0 Weakly correlated
10 ZFP37 11 99.0 Weakly correlated
11 ZNF584 11 99.0 Weakly correlated
12 ZNF554 10 99.0 Weakly correlated
13 ZFP57 10 87.0 Weakly correlated
14 ZNF680 10 28.9 Moderately correlated
15 ZNF197 9 99.0 Weakly correlated
16 ZNF723 9 15.2 Weakly correlated
17 ZNF91 7 6.0 Weakly correlated
18 ZKSCAN8 6 160.0 Weakly correlated
19 ZNF479 6 6.4 Weakly correlated
20 ZFP69B 6 99.0 Weakly correlated
21 ZKSCAN1 6 160.0 Weakly correlated
22 ZNF101 6 43.0 Highly correlated
23 ZNF18 6 160.0 Weakly correlated
24 ZNF133 5 99.0 Weakly correlated
25 ZNF679 5 28.9 Moderately correlated
26 ZNF263 5 180.0 Weakly correlated
27 ZNF486 5 8.6 Weakly correlated
28 ZNF610 4 28.9 Moderately correlated
29 ZNF780A 3 43.0 Highly correlated
30 ZNF793 3 99.0 Weakly correlated
31 ZNF253 3 19.6 Weakly correlated
32 ZIM3 3 87.0 Weakly correlated
33 ZNF141 3 43.0 Highly correlated
34 ZNF701 2 28.9 Moderately correlated
35 ZNF140 2 99.0 Weakly correlated
36 ZNF597 2 94.0 Weakly correlated
37 ZNF558 2 99.0 Weakly correlated
38 ZNF274 2 99.0 Weakly correlated
39 ZNF485 2 94.0 Weakly correlated
40 ZNF425 2 94.0 Weakly correlated
41 ZNF33A 2 99.0 Weakly correlated
42 ZNF41 2 99.0 Weakly correlated
43 ZNF350 2 99.0 Weakly correlated
44 ZNF792 1 94.0 Weakly correlated
45 ZNF765 1 8.6 Weakly correlated
46 RBAK 1 99.0 Weakly correlated
47 ZNF273 1 28.9 Moderately correlated
48 ZNF786 1 99.0 Weakly correlated
49 ZNF324 1 99.0 Weakly correlated
50 ZNF264 1 99.0 Weakly correlated
51 ZNF808 1 19.6 Weakly correlated
52 ZNF816 1 28.9 Moderately correlated
53 ZNF257 1 0.0 Weakly correlated
54 ZNF92 1 28.9 Moderately correlated
55 ZNF284 1 43.0 Highly correlated
56 ZNF695 1 28.9 Moderately correlated
57 ZNF613 1 99.0 Weakly correlated
58 ZNF347 1 43.0 Highly correlated
59 ZKSCAN5 1 160.0 Weakly correlated
60 ZNF585A 1 99.0 Weakly correlated
61 ZNF417 1 28.9 Moderately correlated
62 ZNF557 1 15.2 Weakly correlated
63 ZNF549 1 87.0 Weakly correlated
64 ZNF534 1 19.6 Weakly correlated
65 ZNF44 1 43.0 Highly correlated
KZFPs Motif in Repeats The motif of KZFPs found by the meme-chip appears in the repeats sequence. :
# KZFP name Record number KZFP age(Mya) Time correlation with Repeats
1 ZNF419 28 28.9 Moderately correlated
2 ZNF28 10 28.9 Moderately correlated
3 ZNF723 8 15.2 Weakly correlated
4 ZNF589 7 28.9 Moderately correlated
5 ZNF584 4 99.0 Weakly correlated
6 ZNF175 4 94.0 Weakly correlated
7 ZNF101 3 43.0 Highly correlated
8 ZNF197 3 99.0 Weakly correlated
9 ZFP57 3 87.0 Weakly correlated
10 ZNF554 2 99.0 Weakly correlated
11 ZNF597 2 94.0 Weakly correlated
12 ZNF793 2 99.0 Weakly correlated
13 ZKSCAN1 2 160.0 Weakly correlated
14 ZNF780A 2 43.0 Highly correlated
15 ZNF141 2 43.0 Highly correlated
16 ZNF140 2 99.0 Weakly correlated
17 ZNF274 1 99.0 Weakly correlated
18 ZNF585A 1 99.0 Weakly correlated
19 ZNF808 1 19.6 Weakly correlated
20 ZNF485 1 94.0 Weakly correlated
21 ZNF394 1 99.0 Weakly correlated
22 ZNF347 1 43.0 Highly correlated
23 ZNF816 1 28.9 Moderately correlated
24 ZNF680 1 28.9 Moderately correlated
25 ZNF350 1 99.0 Weakly correlated
26 ZNF534 1 19.6 Weakly correlated
27 ZNF257 1 0.0 Weakly correlated
28 ZKSCAN5 1 160.0 Weakly correlated
29 ZIM3 1 87.0 Weakly correlated
KZFPs Motif in Repeats Consensus The motif of KZFPs found by the meme-chip can find the corresponding region on the consensus sequence of repeats. :
# KZFP name KZFP age(Mya) Time correlation with Repeats
1 ZNF28 28.9 Moderately correlated
2 ZNF589 28.9 Moderately correlated
3 ZNF723 15.2 Weakly correlated