ZRdb KZFP & Repeats
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Human_ZNF888

  • Protein
    Zinc finger protein 888
  • Length
    718
  • Organism
    Homo sapiens (Human)
  • Time of emergence
    28.9 Mya
  • Time of Changing in binding specificity
    28.9 Mya
  • Uniprot_ID
    P0CJ79
  • NCBI_ID
    388559
Sequence:
MALPQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLDISSKCMMEFSSIGKGNTEVIHTGTLQRLASHHIGECCFQEIEKDIHDFVFQWQEDETNGHEAPMTEIKELTGSTDQYDQRHAGNKPIKYQLGSSFHSHLPELHIFQPEGKIGNQLEKSINNASSVSTSQRISCRPKTHISNNYGNNFFHSSLLTQKQDVHRKEKSFQFNESGKSFNCSSLFKKHQIIHLGEKQYKCDVCGKDFNQKRYLAHHRRCHTGEKPYMCNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRVHTGEKPYQCKECDKVFSRKSYLERHRRIHTGEKPYKCKVCDKAFRHDSHLAQHIVIHTREKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSHLAQHTVIHTGEKPYKCNECGKTFVQNSSLVMHKVIHTGEKRYKCNECGKSFNHKSSLAYHHRLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIHRRVHTGEKPYKCRVCDKAFGRDSYLAQHQRVHTGEKPYKCKVCDKAFKCYSHLAQHTRIHTGEKPFKCSECGKAFRAQSTLIHHQAIHGVGKLD
Domain KRAB, ZF, and degenerated ZF domains of KZFPs. :
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# Domain name Pos
1 KRAB 8..79
2 dec2h2 214..236
3 C2h2 242..264
4 C2h2 270..292
5 C2h2 298..320
6 C2h2 326..348
7 C2h2 354..376
8 C2h2 382..404
9 C2h2 410..432
10 C2h2 438..460
11 C2h2 466..488
12 C2h2 494..516
13 C2h2 522..544
14 C2h2 550..572
15 C2h2 578..600
16 C2h2 606..628
17 C2h2 634..656
18 C2h2 662..684
19 C2h2 690..712
Gene Ontology Annotation The Gene Ontology (GO) describes knowledge of the biological domain based on three aspects: Molecular function, Biological process, and Cellular component. :
# Type TERM
1 Cellular Component nucleus
2 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific
3 Molecular Function metal ion binding
4 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding
5 Biological Process regulation of transcription by RNA polymerase II
Is there ChIP-seq data Is there any ChIP-seq data available for these KZFPs in the Cistrome database? :
No
Motif(Predicted) DNA binding motifs predicted using Zinc Finger Recognition Code. :
Forward:
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No Chip-seq
No Chip-seq
No Chip-seq