ZRdb KZFP & Repeats
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Human_ZNF879

  • Protein
    Zinc finger protein 879
  • Length
    563
  • Organism
    Homo sapiens (Human)
  • Time of emergence
    99.0 Mya
  • Time of Changing in binding specificity
    99.0 Mya
  • Uniprot_ID
    B4DU55
  • NCBI_ID
    345462
Sequence:
MARRLLPAHVQESVTFRDVAVFFSQDEWLHLDSAQRALYREVMLENYSILVSLGILFSKPKVISQLEQGEDPWMVESGVPQGAHLGWESLFGTIVSKEENQEVMKKLIIDGTFDFKLEKTYINEDKLEKQQGKKNRLFSKVLVTIKKVYMKERSFKGVEFGKNLGLKSSLIRKPRIVSRGRRPRSQQYSVLFKQLGVNTVRKCYKCNICGKIFLHSSSLSKHQRIHTGEKLYKCKECRKAFSQSSSLTQHLRVHTGEKPYICSECGKAFSFTTSLIGHQRMHTGERPYKCKECGKTFKGSSSLNNHQRIHTGEKPYKCNECGRAFSQCSSLIQHHRIHTGEKPYECTQCGKAFTSISRLSRHHRIHTGEKPFHCNECGKVFSYHSALIIHQRIHTGEKPYACKECGKAFSQSSALIQHQRIHTGEKPYKCNECGKAFSWISRLNIHHRIHTGEKPYNCKECGKAFSSHSGVNTHRKIHTGEKPYKCNDCEKAFNQSSALIQHQRIHTGEKPYNCKVCGKAFRQSSSLMTHMRIHTGEKPYKCKECGKAFSQSSSLTNHQRTHN
Domain KRAB, ZF, and degenerated ZF domains of KZFPs. :
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# Domain name Pos
1 KRAB 14..85
2 C2h2 204..226
3 C2h2 232..254
4 C2h2 260..282
5 C2h2 288..310
6 C2h2 316..338
7 C2h2 344..366
8 C2h2 372..394
9 C2h2 400..422
10 C2h2 428..450
11 C2h2 456..478
12 C2h2 484..506
13 C2h2 512..534
14 C2h2 540..562
Gene Ontology Annotation The Gene Ontology (GO) describes knowledge of the biological domain based on three aspects: Molecular function, Biological process, and Cellular component. :
# Type TERM
1 Cellular Component nucleus
2 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific
3 Molecular Function metal ion binding
4 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding
5 Biological Process regulation of transcription by RNA polymerase II
Is there ChIP-seq data Is there any ChIP-seq data available for these KZFPs in the Cistrome database? :
Yes
Motif(meme-ChIP) DNA binding motifs of KZFPs obtained using meme-ChIP and mapped using pylogo. :
Forward:
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Reverse:
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Peak overlapping A ChIP-seq peak of KZFPs that intersects with a certain repeats sequences on the genome. :
# Repeats name Record number Significance Emergence time(Mya) Time correlation with KZFP
1 L1PB1 66 **** 74.0 Weakly correlated
2 L1M4 51 **** 99.0 Highly correlated
3 L1M1 47 **** 74.0 Weakly correlated
4 AluY 44 **** 74.0 Weakly correlated
5 L1MA3 44 **** 74.0 Weakly correlated
6 AluJb 38 **** 74.0 Weakly correlated
7 L1M5 29 **** 99.0 Highly correlated
8 AluSz 28 ** 74.0 Weakly correlated
9 L1M2 27 **** 99.0 Highly correlated
10 L1MB7 27 **** 99.0 Highly correlated
11 AluSx 25 n.s 74.0 Weakly correlated
12 AluSx1 25 n.s 74.0 Weakly correlated
13 MIRb 23 n.s 99.0 Highly correlated
14 AluJo 20 ** 74.0 Weakly correlated
15 L1MA2 19 **** 74.0 Weakly correlated
16 AluSp 18 ** 74.0 Weakly correlated
17 L2a 17 n.s 99.0 Highly correlated
18 L1MEc 16 **** 99.0 Highly correlated
19 AluSg 15 *** 74.0 Weakly correlated
20 AluSz6 15 ** 74.0 Weakly correlated
21 L1MA4 15 **** 87.0 Weakly correlated
22 L1ME1 15 * 99.0 Highly correlated
23 L1PBa 15 **** 74.0 Weakly correlated
24 MIR 15 n.s 99.0 Highly correlated
25 AluJr 14 n.s 74.0 Weakly correlated
26 L1M4b 14 **** 99.0 Highly correlated
27 L1MA4A 13 **** 87.0 Weakly correlated
28 L1MB5 13 **** 99.0 Highly correlated
29 L1MDa 13 **** 99.0 Highly correlated
30 L2c 13 n.s 99.0 Highly correlated
31 L1MA9 12 *** 99.0 Highly correlated
32 L1MB8 12 *** 99.0 Highly correlated
33 L1MD1 12 **** 99.0 Highly correlated
34 MIRc 12 * 99.0 Highly correlated
35 FLAM_C 11 **** 74.0 Weakly correlated
36 L1M4c 11 **** 99.0 Highly correlated
37 L1MCa 11 **** 99.0 Highly correlated
38 AluSq2 10 n.s 74.0 Weakly correlated
39 L1PBa1 10 **** 74.0 Weakly correlated
40 AluSx3 9 * 74.0 Weakly correlated
41 L1MEf 9 ** 99.0 Highly correlated
42 AluSc8 8 * 74.0 Weakly correlated
43 L1MC4 8 n.s 99.0 Highly correlated
44 L1ME3A 8 ** 99.0 Highly correlated
45 L1MEd 8 * 99.0 Highly correlated
46 AluSc 7 n.s 74.0 Weakly correlated
47 L1MA5 7 *** 87.0 Weakly correlated
48 L1MB3 7 n.s 99.0 Highly correlated
49 L1MD 7 *** 99.0 Highly correlated
50 L1PB3 7 *** 74.0 Weakly correlated
51 L1M3 6 *** 99.0 Highly correlated
52 L1MB4 6 ** 99.0 Highly correlated
53 L1MEg 6 n.s 99.0 Highly correlated
54 L1PB4 6 * 99.0 Highly correlated
55 L2b 6 n.s 99.0 Highly correlated
56 L1M4a2 5 **** 99.0 Highly correlated
57 L1MA5A 5 *** 87.0 Weakly correlated
58 L1MA8 5 n.s 87.0 Weakly correlated
59 L1MC 5 ** 99.0 Highly correlated
60 L1MC1 5 n.s 99.0 Highly correlated
61 L1MC2 5 * 99.0 Highly correlated
62 L1MC4a 5 * 99.0 Highly correlated
63 L1PA16 5 n.s 74.0 Weakly correlated
64 L1PA7 5 n.s 74.0 Weakly correlated
65 MIR3 5 n.s 99.0 Highly correlated
66 L1MA1 4 n.s 74.0 Weakly correlated
67 L1MA7 4 n.s 87.0 Weakly correlated
68 L1MB1 4 * 99.0 Highly correlated
69 L1MB2 4 n.s 99.0 Highly correlated
70 L1MC5 4 n.s 99.0 Highly correlated
71 L1MD2 4 n.s 99.0 Highly correlated
72 L1ME2 4 n.s 99.0 Highly correlated
73 L1ME4a 4 n.s 99.0 Highly correlated
74 L1PA17 4 * 74.0 Weakly correlated
75 L1PA5 4 n.s 19.6 Weakly correlated
76 L3 4 n.s 99.0 Highly correlated
77 LTR10A 4 **** 28.9 Weakly correlated
78 MLT1D 4 n.s 99.0 Highly correlated
79 AluJr4 3 n.s 74.0 Weakly correlated
80 AluSq 3 n.s 74.0 Weakly correlated
81 L1M2c 3 **** 87.0 Weakly correlated
82 L1M3c 3 *** 99.0 Highly correlated
83 L1MA10 3 * 99.0 Highly correlated
84 L1MA6 3 n.s 87.0 Weakly correlated
85 L1MD3 3 * 99.0 Highly correlated
86 L1ME3 3 n.s 99.0 Highly correlated
87 L1ME3Cz 3 n.s 99.0 Highly correlated
88 L1ME3G 3 n.s 99.0 Highly correlated
89 L1ME4b 3 n.s 99.0 Highly correlated
90 L1P3 3 n.s 74.0 Weakly correlated
91 L1P4 3 * 74.0 Weakly correlated
92 L1PA15 3 n.s 74.0 Weakly correlated
93 L1PA4 3 n.s 19.6 Weakly correlated
94 L1PA8 3 n.s 74.0 Weakly correlated
95 L2 3 n.s 99.0 Highly correlated
96 MER90a 3 **** 99.0 Highly correlated
97 MLT1A0 3 n.s 99.0 Highly correlated
98 AluSc5 2 n.s 74.0 Weakly correlated
99 AluYc 2 * 74.0 Weakly correlated
100 AluYh3 2 ** 15.2 Weakly correlated
101 AluYm1 2 * 19.6 Weakly correlated
102 FLAM_A 2 n.s 74.0 Weakly correlated
103 FRAM 2 * 74.0 Weakly correlated
104 HAL1 2 n.s 99.0 Highly correlated
105 L1M3de 2 *** 99.0 Highly correlated
106 L1MC3 2 n.s 99.0 Highly correlated
107 L1MDb 2 ** 99.0 Highly correlated
108 L1ME3C 2 * 99.0 Highly correlated
109 L1ME3E 2 n.s 99.0 Highly correlated
110 L1P1 2 n.s 19.6 Weakly correlated
111 L1PA11 2 n.s 74.0 Weakly correlated
112 L1PA15-16 2 n.s 74.0 Weakly correlated
113 L1PA2 2 n.s 15.2 Weakly correlated
114 L1PA6 2 n.s 28.9 Weakly correlated
115 L1PB 2 * 74.0 Weakly correlated
116 L1PB2 2 n.s 74.0 Weakly correlated
117 L1PBb 2 ** 74.0 Weakly correlated
118 L1PREC2 2 n.s 43.0 Weakly correlated
119 LTR13 2 ** 19.6 Weakly correlated
120 MER4-int 2 n.s 74.0 Weakly correlated
121 MER50 2 * 43.0 Weakly correlated
122 MLT1A1 2 n.s 87.0 Weakly correlated
123 MLT1E1A 2 * 99.0 Highly correlated
124 Alu 1 ** 74.0 Weakly correlated
125 AluSg4 1 n.s 74.0 Weakly correlated
126 AluSg7 1 n.s 74.0 Weakly correlated
127 AluSq10 1 * 74.0 Weakly correlated
128 AluSq4 1 * 74.0 Weakly correlated
129 AluSx4 1 n.s 74.0 Weakly correlated
130 AluYa5 1 n.s 15.2 Weakly correlated
131 AluYa8 1 *** 15.2 Weakly correlated
132 AluYc3 1 ** 74.0 Weakly correlated
133 AluYh9 1 **** 15.2 Weakly correlated
134 AluYj4 1 n.s 0.0 Weakly correlated
135 ERVL-B4-int 1 n.s 99.0 Highly correlated
136 HAL1M8 1 n.s 99.0 Highly correlated
137 HERV4_I-int 1 ** 43.0 Weakly correlated
138 L1M2a 1 * 87.0 Weakly correlated
139 L1M3b 1 * 99.0 Highly correlated
140 L1M3e 1 * 99.0 Highly correlated
141 L1M4a1 1 n.s 99.0 Highly correlated
142 L1M7 1 n.s 99.0 Highly correlated
143 L1MC5a 1 n.s 99.0 Highly correlated
144 L1MCc 1 n.s 99.0 Highly correlated
145 L1ME2z 1 n.s 99.0 Highly correlated
146 L1ME3B 1 n.s 99.0 Highly correlated
147 L1ME3D 1 n.s 99.0 Highly correlated
148 L1MEa 1 ** 99.0 Highly correlated
149 L1MEb 1 n.s 99.0 Highly correlated
150 L1MEi 1 n.s 99.0 Highly correlated
151 L1MEj 1 n.s 99.0 Highly correlated
152 L1P2 1 n.s 28.9 Weakly correlated
153 L1P4a 1 n.s 74.0 Weakly correlated
154 L1PA3 1 n.s 19.6 Weakly correlated
155 L1PA8A 1 n.s 74.0 Weakly correlated
156 L2-3_Crp 1 * 431.0 Weakly correlated
157 L4_A_Mam 1 n.s 99.0 Highly correlated
158 LTR10F 1 ** 28.9 Weakly correlated
159 LTR12 1 * 28.9 Weakly correlated
160 LTR16A2 1 * 99.0 Highly correlated
161 LTR16B 1 ** 99.0 Highly correlated
162 LTR16C 1 n.s 99.0 Highly correlated
163 LTR1A2 1 * 43.0 Weakly correlated
164 LTR23 1 ** 74.0 Weakly correlated
165 LTR33 1 n.s 99.0 Highly correlated
166 LTR33A_ 1 * 99.0 Highly correlated
167 LTR40a 1 n.s 99.0 Highly correlated
168 LTR47A 1 ** 74.0 Weakly correlated
169 LTR71B 1 ** 43.0 Weakly correlated
170 LTR79 1 n.s 99.0 Highly correlated
171 LTR82B 1 * 99.0 Highly correlated
172 LTR8A 1 n.s 43.0 Weakly correlated
173 MER21C 1 n.s 99.0 Highly correlated
174 MER31B 1 * 99.0 Highly correlated
175 MER34C2 1 ** 74.0 Weakly correlated
176 MER39B 1 * 74.0 Weakly correlated
177 MER4E 1 * 74.0 Weakly correlated
178 MER50-int 1 * 43.0 Weakly correlated
179 MER57B1 1 * 43.0 Weakly correlated
180 MER66B 1 * 43.0 Weakly correlated
181 MER68 1 * 99.0 Highly correlated
182 MER77 1 * 99.0 Highly correlated
183 MER77B 1 * 99.0 Highly correlated
184 MLT1A 1 n.s 99.0 Highly correlated
185 MLT1B 1 n.s 99.0 Highly correlated
186 MLT1C 1 n.s 94.0 Weakly correlated
187 MLT1F1 1 n.s 99.0 Highly correlated
188 MLT1G 1 n.s 99.0 Highly correlated
189 MLT1K 1 n.s 99.0 Highly correlated
190 MSTA 1 n.s 43.0 Weakly correlated
191 MSTB1 1 n.s 74.0 Weakly correlated
192 MSTB2 1 * 74.0 Weakly correlated
193 MamRTE1 1 n.s 99.0 Highly correlated
194 MamRep1527 1 * 99.0 Highly correlated
195 SVA_A 1 * 19.6 Weakly correlated
196 SVA_C 1 * 15.2 Weakly correlated
197 SVA_E 1 * 0.0 Weakly correlated
Motif in Repeats The motif of KZFPs identified by the MEME-ChIP is present in repeats sequences. :
# Repeats name Record number Significance Emergence time(Mya) Time correlation with KZFP
1 L1PB1 59 **** 74.0 Weakly correlated
2 L1M4 41 **** 99.0 Highly correlated
3 L1M1 40 **** 74.0 Weakly correlated
4 L1MA3 38 **** 74.0 Weakly correlated
5 L1M2 19 **** 99.0 Highly correlated
6 L1MB7 18 **** 99.0 Highly correlated
7 L1MA2 17 **** 74.0 Weakly correlated
8 L1PBa 14 **** 74.0 Weakly correlated
9 L1M5 13 n.s 99.0 Highly correlated
10 L1M4b 13 **** 99.0 Highly correlated
11 L1MA4 12 *** 87.0 Weakly correlated
12 L1MDa 11 **** 99.0 Highly correlated
13 L1MEc 11 ** 99.0 Highly correlated
14 L1MCa 10 **** 99.0 Highly correlated
15 L1PBa1 10 **** 74.0 Weakly correlated
16 L1MB5 9 *** 99.0 Highly correlated
17 L1MA4A 9 *** 87.0 Weakly correlated
18 L1MD1 8 *** 99.0 Highly correlated
19 L1M4c 8 **** 99.0 Highly correlated
20 L1MB8 8 * 99.0 Highly correlated
21 MIRb 7 n.s 99.0 Highly correlated
22 L1PB3 7 *** 74.0 Weakly correlated
23 L1MB4 6 ** 99.0 Highly correlated
24 L1MEg 6 n.s 99.0 Highly correlated
25 L1ME1 6 n.s 99.0 Highly correlated
26 L1MEd 6 n.s 99.0 Highly correlated
27 L1ME3A 6 n.s 99.0 Highly correlated
28 L1MA9 6 n.s 99.0 Highly correlated
29 L1M3 5 ** 99.0 Highly correlated
30 L1MD 5 ** 99.0 Highly correlated
31 L1MB3 5 n.s 99.0 Highly correlated
32 L1MEf 5 n.s 99.0 Highly correlated
33 L1MB1 4 * 99.0 Highly correlated
34 L1PA17 4 * 74.0 Weakly correlated
35 L1MA8 4 n.s 87.0 Weakly correlated
36 L1PB4 4 n.s 99.0 Highly correlated
37 L1M4a2 3 ** 99.0 Highly correlated
38 L1MA5 3 n.s 87.0 Weakly correlated
39 L1PA7 3 n.s 74.0 Weakly correlated
40 MIR 3 n.s 99.0 Highly correlated
41 L1MA1 3 n.s 74.0 Weakly correlated
42 L1MC 3 * 99.0 Highly correlated
43 L1ME3Cz 3 n.s 99.0 Highly correlated
44 L1MA5A 3 * 87.0 Weakly correlated
45 L1MA7 3 n.s 87.0 Weakly correlated
46 L1PA15 2 n.s 74.0 Weakly correlated
47 MLT1D 2 n.s 99.0 Highly correlated
48 MIRc 2 n.s 99.0 Highly correlated
49 L2a 2 n.s 99.0 Highly correlated
50 L1MC4 2 n.s 99.0 Highly correlated
51 L1M3c 2 ** 99.0 Highly correlated
52 L1MA6 2 n.s 87.0 Weakly correlated
53 L1PA15-16 2 n.s 74.0 Weakly correlated
54 L1M2c 2 *** 87.0 Weakly correlated
55 L1MD2 2 n.s 99.0 Highly correlated
56 L1MB2 2 n.s 99.0 Highly correlated
57 L1PB2 2 n.s 74.0 Weakly correlated
58 L1PB 2 * 74.0 Weakly correlated
59 AluSx3 1 n.s 74.0 Weakly correlated
60 L1PA5 1 n.s 19.6 Weakly correlated
61 L1M3b 1 * 99.0 Highly correlated
62 MIR3 1 n.s 99.0 Highly correlated
63 LTR23 1 ** 74.0 Weakly correlated
64 L1ME4b 1 n.s 99.0 Highly correlated
65 AluJr4 1 n.s 74.0 Weakly correlated
66 L1MC1 1 n.s 99.0 Highly correlated
67 L1MEa 1 ** 99.0 Highly correlated
68 L1M4a1 1 n.s 99.0 Highly correlated
69 L1MC3 1 n.s 99.0 Highly correlated
70 L1ME2 1 n.s 99.0 Highly correlated
71 L1PA8 1 n.s 74.0 Weakly correlated
72 L1PREC2 1 n.s 43.0 Weakly correlated
73 L1M7 1 n.s 99.0 Highly correlated
74 L1MC4a 1 n.s 99.0 Highly correlated
75 L1MEj 1 n.s 99.0 Highly correlated
76 L1P1 1 n.s 19.6 Weakly correlated
77 AluSz6 1 n.s 74.0 Weakly correlated
78 L1MC5a 1 n.s 99.0 Highly correlated
79 L1ME3G 1 n.s 99.0 Highly correlated
80 L1PA11 1 n.s 74.0 Weakly correlated
81 L1M3de 1 * 99.0 Highly correlated
82 L1MA10 1 n.s 99.0 Highly correlated
83 L1MC2 1 n.s 99.0 Highly correlated
84 L1PA4 1 n.s 19.6 Weakly correlated
85 L1PBb 1 * 74.0 Weakly correlated
86 L1PA16 1 n.s 74.0 Weakly correlated
87 AluSp 1 n.s 74.0 Weakly correlated
88 L1M3e 1 * 99.0 Highly correlated
89 L1MC5 1 n.s 99.0 Highly correlated
90 L1MD3 1 n.s 99.0 Highly correlated
91 L1ME4a 1 n.s 99.0 Highly correlated
92 LTR79 1 n.s 99.0 Highly correlated
93 AluJr 1 n.s 74.0 Weakly correlated
94 AluSc 1 n.s 74.0 Weakly correlated
95 L1MDb 1 * 99.0 Highly correlated
96 MLT1A0 1 n.s 99.0 Highly correlated
97 MamRep1527 1 * 99.0 Highly correlated
98 AluJb 1 n.s 74.0 Weakly correlated
99 AluSx 1 n.s 74.0 Weakly correlated
Motif in Repeats Consensus The motif of KZFPs identified by MEME-ChIP analysis can be utilized to locate the corresponding region within the consensus sequences of repeats. :
# Repeats name Emergence time(Mya) Time correlation with KZFP