ZRdb KZFP & Repeats
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Human_ZNF799

  • Protein
    Zinc finger protein 799
  • Length
    643
  • Organism
    Homo sapiens (Human)
  • Time of emergence
    69.0 Mya
  • Time of Changing in binding specificity
    43.0 Mya
  • Uniprot_ID
    Q96GE5
  • NCBI_ID
    90576
Sequence:
MASVALEDVAVNFTREEWALLGPCQKNLYKDVMQETIRNLDCVGMKWKDQNIEDQYRYPRKNLRCRMLERFVESKDGTQCGETSSQIQDSIVTKNTLPGVGPYESRMSGEVIMGHSSLNCYIRVGAGHKPYEYHECGEKPDTHKQRGKAFSYHNSLQTHERLHTGKKPYNCKECGKSFSSLGNLQRHMAVQRGDGPYKCKLCGKAFFWPSLLHMHERTHTGEKPYECKQCSKAFSFYSSYLRHERTHTGEKLYECKQCSKAFPDYSSCLRHERTHTGKKPYTCKQCGKAFSASTSLRRHETTHTDEKPYACQQCGKAFHHLGSFQRHMVMHTRDGPHKCKICGKGFDCPSSLKSHERTHTGEKLYECKQCGKALSHSSSFRRHMTMHTGDGPHKCKICGKAFVYPSVFQRHEKTHTAEKPYKCKQCGKAYRISSSLRRHETTHTGEKPYKCKCGKAFIDFYSFQNHKTTHAGEKPYECKECGKAFSCFQYLSQHRRTHTGEKPYECNTCKKAFSHFGNLKVHERIHSGEKPYECKECGKAFSWLTCFLRHERIHMREKPYECQQCGKAFTHSRFLQGHEKTHTGENPYECKECGKAFASLSSLHRHKKTHWKKTHTGENPYGCKECGKAFASLSSLHRHKKTH
Domain KRAB, ZF, and degenerated ZF domains of KZFPs. :
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# Domain name Pos
1 KRAB 4..86
2 dec2h2 134..163
3 dec2h2 169..191
4 C2h2 197..219
5 C2h2 225..247
6 C2h2 253..275
7 C2h2 281..303
8 C2h2 309..331
9 C2h2 337..359
10 C2h2 365..387
11 C2h2 393..415
12 C2h2 421..443
13 C2h2 449..470
14 C2h2 476..498
15 C2h2 504..526
16 C2h2 532..554
17 C2h2 560..582
18 C2h2 588..615
19 C2h2 621..643
Gene Ontology Annotation The Gene Ontology (GO) describes knowledge of the biological domain based on three aspects: Molecular function, Biological process, and Cellular component. :
# Type TERM
1 Cellular Component nucleus
2 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific
3 Molecular Function metal ion binding
4 Molecular Function RNA polymerase II transcription regulatory region sequence-specific DNA binding
5 Biological Process regulation of transcription by RNA polymerase II
Is there ChIP-seq data Is there any ChIP-seq data available for these KZFPs in the Cistrome database? :
Yes
Motif(meme-ChIP) DNA binding motifs of KZFPs obtained using meme-ChIP and mapped using pylogo. :
Forward:
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Reverse:
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Peak overlapping A ChIP-seq peak of KZFPs that intersects with a certain repeats sequences on the genome. :
# Repeats name Record number Significance Emergence time(Mya) Time correlation with KZFP
1 LOR1b 101 **** 74.0 Weakly correlated
2 LOR1a 87 **** 74.0 Weakly correlated
3 LTR8B 69 **** 43.0 Highly correlated
4 LTR26 17 **** 74.0 Weakly correlated
5 AluJb 16 * 74.0 Weakly correlated
6 L2a 13 n.s 99.0 Weakly correlated
7 LTR8 10 **** 43.0 Highly correlated
8 L2c 9 n.s 99.0 Weakly correlated
9 MIRb 9 n.s 99.0 Weakly correlated
10 L2 8 * 99.0 Weakly correlated
11 LTR13 8 **** 19.6 Weakly correlated
12 LOR1-int 7 **** 74.0 Weakly correlated
13 AluSx 6 n.s 74.0 Weakly correlated
14 L1ME1 6 n.s 99.0 Weakly correlated
15 LTR38A1 6 **** 74.0 Weakly correlated
16 MER87B 6 **** 74.0 Weakly correlated
17 MIRc 6 n.s 99.0 Weakly correlated
18 AluY 5 n.s 74.0 Weakly correlated
19 L1M5 5 n.s 99.0 Weakly correlated
20 L1MC4 5 * 99.0 Weakly correlated
21 MIR 5 n.s 99.0 Weakly correlated
22 MLT1H 5 *** 99.0 Weakly correlated
23 AluJr 4 n.s 74.0 Weakly correlated
24 AluSg 4 n.s 74.0 Weakly correlated
25 L1PA5 4 n.s 19.6 Weakly correlated
26 L3 4 n.s 99.0 Weakly correlated
27 LTR10A 4 **** 28.9 Weakly correlated
28 LTR26C 4 **** 0.0 Weakly correlated
29 AluSc8 3 n.s 74.0 Weakly correlated
30 AluSp 3 n.s 74.0 Weakly correlated
31 AluSq2 3 n.s 74.0 Weakly correlated
32 AluSx1 3 n.s 74.0 Weakly correlated
33 AluSz 3 n.s 74.0 Weakly correlated
34 HAL1 3 n.s 99.0 Weakly correlated
35 L1MA9 3 n.s 99.0 Weakly correlated
36 L1MC1 3 n.s 99.0 Weakly correlated
37 LTR16A 3 *** 99.0 Weakly correlated
38 LTR31 3 **** 74.0 Weakly correlated
39 MLT1B 3 n.s 99.0 Weakly correlated
40 MLT1D 3 n.s 99.0 Weakly correlated
41 AluSx3 2 n.s 74.0 Weakly correlated
42 AluYm1 2 ** 19.6 Weakly correlated
43 FLAM_C 2 n.s 74.0 Weakly correlated
44 L1M4 2 n.s 99.0 Weakly correlated
45 L1MB3 2 n.s 99.0 Weakly correlated
46 L1MDa 2 n.s 99.0 Weakly correlated
47 L1ME3B 2 n.s 99.0 Weakly correlated
48 L1ME3D 2 * 99.0 Weakly correlated
49 L1ME4a 2 n.s 99.0 Weakly correlated
50 L1MEc 2 n.s 99.0 Weakly correlated
51 L1PA17 2 n.s 74.0 Weakly correlated
52 L1PB1 2 n.s 74.0 Weakly correlated
53 L1PB2 2 * 74.0 Weakly correlated
54 L2b 2 n.s 99.0 Weakly correlated
55 LTR26E 2 **** 74.0 Weakly correlated
56 MER21C 2 * 99.0 Weakly correlated
57 MER68 2 *** 99.0 Weakly correlated
58 MIR3 2 n.s 99.0 Weakly correlated
59 MLT1A0 2 n.s 99.0 Weakly correlated
60 MLT1F 2 ** 99.0 Weakly correlated
61 MLT2C1 2 *** 99.0 Weakly correlated
62 MLT2D 2 ** 99.0 Weakly correlated
63 THE1B-int 2 n.s 43.0 Highly correlated
64 AluJo 1 n.s 74.0 Weakly correlated
65 AluJr4 1 n.s 74.0 Weakly correlated
66 AluSc5 1 n.s 74.0 Weakly correlated
67 AluSg7 1 n.s 74.0 Weakly correlated
68 AluSq 1 n.s 74.0 Weakly correlated
69 AluSz6 1 n.s 74.0 Weakly correlated
70 AluYa5 1 * 15.2 Weakly correlated
71 AluYc 1 * 74.0 Weakly correlated
72 AluYk11 1 *** 15.2 Weakly correlated
73 ERVL-E-int 1 n.s 99.0 Weakly correlated
74 ERVL-int 1 * 99.0 Weakly correlated
75 FRAM 1 * 74.0 Weakly correlated
76 HAL1ME 1 n.s 99.0 Weakly correlated
77 HERV16-int 1 * 99.0 Weakly correlated
78 HERVH-int 1 n.s 28.9 Weakly correlated
79 HERVIP10B3-int 1 ** 28.9 Weakly correlated
80 HERVL-int 1 n.s 74.0 Weakly correlated
81 L1M2 1 n.s 99.0 Weakly correlated
82 L1M3b 1 ** 99.0 Weakly correlated
83 L1M4a2 1 * 99.0 Weakly correlated
84 L1MA2 1 n.s 74.0 Weakly correlated
85 L1MA3 1 n.s 74.0 Weakly correlated
86 L1MA5 1 n.s 87.0 Weakly correlated
87 L1MA6 1 n.s 87.0 Weakly correlated
88 L1MA7 1 n.s 87.0 Weakly correlated
89 L1MB2 1 n.s 99.0 Weakly correlated
90 L1MB4 1 n.s 99.0 Weakly correlated
91 L1MB5 1 n.s 99.0 Weakly correlated
92 L1MB7 1 n.s 99.0 Weakly correlated
93 L1MC2 1 n.s 99.0 Weakly correlated
94 L1MC3 1 n.s 99.0 Weakly correlated
95 L1MC4a 1 n.s 99.0 Weakly correlated
96 L1MC5a 1 n.s 99.0 Weakly correlated
97 L1MCb 1 * 99.0 Weakly correlated
98 L1MD 1 n.s 99.0 Weakly correlated
99 L1MD1 1 n.s 99.0 Weakly correlated
100 L1MD2 1 n.s 99.0 Weakly correlated
101 L1MDb 1 * 99.0 Weakly correlated
102 L1ME3A 1 n.s 99.0 Weakly correlated
103 L1ME3Cz 1 n.s 99.0 Weakly correlated
104 L1ME3E 1 n.s 99.0 Weakly correlated
105 L1ME3F 1 n.s 99.0 Weakly correlated
106 L1ME3G 1 n.s 99.0 Weakly correlated
107 L1ME4b 1 n.s 99.0 Weakly correlated
108 L1ME5 1 * 99.0 Weakly correlated
109 L1MEd 1 n.s 99.0 Weakly correlated
110 L1MEh 1 * 99.0 Weakly correlated
111 L1P1 1 n.s 19.6 Weakly correlated
112 L1PA13 1 n.s 74.0 Weakly correlated
113 L1PA2 1 n.s 15.2 Weakly correlated
114 L1PA4 1 n.s 19.6 Weakly correlated
115 L2-3_Crp 1 ** 431.0 Weakly correlated
116 L3b 1 n.s 99.0 Weakly correlated
117 LTR28 1 *** 43.0 Highly correlated
118 LTR29 1 ** 43.0 Highly correlated
119 LTR36 1 ** 74.0 Weakly correlated
120 LTR41 1 ** 99.0 Weakly correlated
121 LTR42 1 *** 74.0 Weakly correlated
122 LTR45C 1 *** 99.0 Weakly correlated
123 LTR54 1 ** 74.0 Weakly correlated
124 LTR5A 1 ** 19.6 Weakly correlated
125 LTR71B 1 *** 43.0 Highly correlated
126 LTR72 1 *** 74.0 Weakly correlated
127 LTR7B 1 ** 28.9 Weakly correlated
128 LTR9D 1 ** 43.0 Highly correlated
129 MER21-int 1 * 99.0 Weakly correlated
130 MER34B-int 1 ** 99.0 Weakly correlated
131 MER34C2 1 ** 74.0 Weakly correlated
132 MER34C_ 1 ** 87.0 Weakly correlated
133 MER39B 1 ** 74.0 Weakly correlated
134 MER4-int 1 n.s 74.0 Weakly correlated
135 MER4A1 1 * 74.0 Weakly correlated
136 MER4D1 1 * 74.0 Weakly correlated
137 MER50 1 * 43.0 Highly correlated
138 MER50-int 1 ** 43.0 Highly correlated
139 MER57B2 1 ** 43.0 Highly correlated
140 MER61B 1 *** 43.0 Highly correlated
141 MER66B 1 ** 43.0 Highly correlated
142 MER74A 1 * 99.0 Weakly correlated
143 MER77 1 * 99.0 Weakly correlated
144 MER87 1 *** 43.0 Highly correlated
145 MLT1A 1 n.s 99.0 Weakly correlated
146 MLT1C 1 n.s 94.0 Weakly correlated
147 MLT1E1A 1 * 99.0 Weakly correlated
148 MLT1E3 1 * 99.0 Weakly correlated
149 MLT1G1 1 * 99.0 Weakly correlated
150 MLT1H1 1 * 99.0 Weakly correlated
151 MLT1H1-int 1 ** 99.0 Weakly correlated
152 MLT1J 1 n.s 99.0 Weakly correlated
153 MLT1J2 1 n.s 99.0 Weakly correlated
154 MLT1K 1 n.s 99.0 Weakly correlated
155 MLT1M 1 ** 99.0 Weakly correlated
156 MLT1N2 1 * 99.0 Weakly correlated
157 MLT2B1 1 n.s 99.0 Weakly correlated
158 MSTB1-int 1 ** 74.0 Weakly correlated
159 MSTD 1 n.s 74.0 Weakly correlated
160 MamRTE1 1 n.s 99.0 Weakly correlated
161 THE1A-int 1 n.s 43.0 Highly correlated
162 THE1B 1 n.s 43.0 Highly correlated
163 THE1C-int 1 n.s 43.0 Highly correlated
164 THE1D 1 n.s 43.0 Highly correlated
Motif in Repeats The motif of KZFPs identified by the MEME-ChIP is present in repeats sequences. :
# Repeats name Record number Significance Emergence time(Mya) Time correlation with KZFP
1 LOR1b 99 **** 74.0 Weakly correlated
2 LOR1a 83 **** 74.0 Weakly correlated
3 LTR8B 44 **** 43.0 Highly correlated
4 LTR26 14 **** 74.0 Weakly correlated
5 LTR8 5 **** 43.0 Highly correlated
6 LTR26C 4 **** 0.0 Weakly correlated
7 MER87B 3 **** 74.0 Weakly correlated
8 LTR31 3 **** 74.0 Weakly correlated
9 LTR38A1 2 **** 74.0 Weakly correlated
10 L2a 2 n.s 99.0 Weakly correlated
11 THE1B-int 2 n.s 43.0 Highly correlated
12 AluSx 2 n.s 74.0 Weakly correlated
13 L1MDb 1 * 99.0 Weakly correlated
14 L3 1 n.s 99.0 Weakly correlated
15 HAL1 1 n.s 99.0 Weakly correlated
16 L1ME5 1 * 99.0 Weakly correlated
17 L1PA4 1 n.s 19.6 Weakly correlated
18 L1PA13 1 n.s 74.0 Weakly correlated
19 MIRb 1 n.s 99.0 Weakly correlated
20 MER77 1 * 99.0 Weakly correlated
21 L1MA9 1 n.s 99.0 Weakly correlated
22 L1M5 1 n.s 99.0 Weakly correlated
23 MSTB1-int 1 ** 74.0 Weakly correlated
24 MER68 1 * 99.0 Weakly correlated
25 AluJb 1 n.s 74.0 Weakly correlated
26 L1MEh 1 * 99.0 Weakly correlated
27 L1MEc 1 n.s 99.0 Weakly correlated
28 THE1C-int 1 n.s 43.0 Highly correlated
29 LTR26E 1 **** 74.0 Weakly correlated
30 LTR16A 1 * 99.0 Weakly correlated
31 L1PA5 1 n.s 19.6 Weakly correlated
32 L1MA7 1 n.s 87.0 Weakly correlated
33 AluSc8 1 n.s 74.0 Weakly correlated
Motif in Repeats Consensus The motif of KZFPs identified by MEME-ChIP analysis can be utilized to locate the corresponding region within the consensus sequences of repeats. :
# Repeats name Emergence time(Mya) Time correlation with KZFP
1 LOR1A 74.0 Weakly correlated
2 LOR1B 74.0 Weakly correlated
3 LTR26 74.0 Weakly correlated
4 LTR8B 43.0 Highly correlated