ZRdb KZFP & Repeats
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Human_ZNF747

  • Protein
    Zinc finger protein 747
  • Length
    330
  • Organism
    Homo sapiens (Human)
  • Time of emergence
    99.0 Mya
  • Time of Changing in binding specificity
    43.0 Mya
  • Uniprot_ID
  • NCBI_ID
Sequence:
MTDPSLGLTVPMAPPLAPLPPRDPNGAGSEWRKPGAVSFADVAVYFSREEWGCLRPAQRALYRDVMRETYGHLGALGVGGSKPALISWVEEKAELWDPAAQDPEVAKCPTEADPDSRNKEEERQREGTGALEKPDPVAAGSPGLKAPQAPFAGLEQLSKARRRSRPRFFAHPPVPRADQRHGCYVCGKSFAWRSTLVEHIYSHRGEKPFHCADCGKGFGHASSLSKHRAIHRGERPHRCPECGRAFMRRTALTSHLRVHTGEKPYRCPQCGRCFGLKTGMAKHQWVHRPGGEGRRGRRPGGLSVTLTPVRGDLDPPVGFQLYPEIFQECG
Domain KRAB, ZF, and degenerated ZF domains of KZFPs. :
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# Domain name Pos
1 KRAB 37..108
2 C2h2 181..203
3 C2h2 209..231
4 C2h2 237..259
5 C2h2 265..287
Gene Ontology Annotation The Gene Ontology (GO) describes knowledge of the biological domain based on three aspects: Molecular function, Biological process, and Cellular component. :
# Type TERM
1 Cellular Component
2 Molecular Function metal ion binding
3 Biological Process regulation of DNA-templated transcription
Is there ChIP-seq data Is there any ChIP-seq data available for these KZFPs in the Cistrome database? :
Yes
Motif(meme-ChIP) DNA binding motifs of KZFPs obtained using meme-ChIP and mapped using pylogo. :
Forward:
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Reverse:
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Peak overlapping A ChIP-seq peak of KZFPs that intersects with a certain repeats sequences on the genome. :
# Repeats name Record number Significance Emergence time(Mya) Time correlation with KZFP
1 AluJb 20 n.s 74.0 Weakly correlated
2 SVA_F 12 **** 0.0 Weakly correlated
3 L1P3 11 **** 74.0 Weakly correlated
4 SVA_D 10 **** 15.2 Weakly correlated
5 AluY 9 n.s 74.0 Weakly correlated
6 LTR8 9 **** 43.0 Highly correlated
7 LTR12C 8 *** 19.6 Weakly correlated
8 AluSc8 7 * 74.0 Weakly correlated
9 AluSp 6 n.s 74.0 Weakly correlated
10 HUERS-P2-int 6 **** 43.0 Highly correlated
11 LTR41 6 **** 99.0 Weakly correlated
12 AluJo 4 n.s 74.0 Weakly correlated
13 L2c 4 n.s 99.0 Weakly correlated
14 LTR10A 4 **** 28.9 Weakly correlated
15 AluYj4 4 **** 0.0 Weakly correlated
16 MER21B 3 ** 99.0 Weakly correlated
17 ERV3-16A3_I-int 3 n.s 99.0 Weakly correlated
18 FRAM 3 ** 74.0 Weakly correlated
19 LTR13 3 *** 19.6 Weakly correlated
20 MIRb 3 n.s 99.0 Weakly correlated
21 L1HS 3 n.s 8.6 Weakly correlated
22 L1PA3 2 n.s 19.6 Weakly correlated
23 L1P4 2 n.s 74.0 Weakly correlated
24 L1PA2 2 n.s 15.2 Weakly correlated
25 THE1B-int 2 n.s 43.0 Highly correlated
26 L1PA5 2 n.s 19.6 Weakly correlated
27 L2a 2 n.s 99.0 Weakly correlated
28 SVA_E 2 *** 0.0 Weakly correlated
29 MIRc 2 n.s 99.0 Weakly correlated
30 LTR10F 2 *** 28.9 Weakly correlated
31 MER52A 2 n.s 74.0 Weakly correlated
32 MER39B 2 ** 74.0 Weakly correlated
33 AluSc 2 n.s 74.0 Weakly correlated
34 L1M4 2 n.s 99.0 Weakly correlated
35 MLT1B 1 n.s 99.0 Weakly correlated
36 LTR41C 1 ** 99.0 Weakly correlated
37 LTR46 1 *** 43.0 Highly correlated
38 LTR50 1 n.s 99.0 Weakly correlated
39 LTR71B 1 ** 43.0 Highly correlated
40 AluYk3 1 * 19.6 Weakly correlated
41 AluYh9 1 **** 15.2 Weakly correlated
42 AluYa8 1 *** 15.2 Weakly correlated
43 AluYa5 1 n.s 15.2 Weakly correlated
44 MIR 1 n.s 99.0 Weakly correlated
45 AluSz 1 n.s 74.0 Weakly correlated
46 AluSx1 1 n.s 74.0 Weakly correlated
47 LTR28C 1 ** 43.0 Highly correlated
48 MLT1K 1 n.s 99.0 Weakly correlated
49 MLT1L 1 n.s 99.0 Weakly correlated
50 MamGyp-int 1 ** 99.0 Weakly correlated
51 SVA_A 1 * 19.6 Weakly correlated
52 AluSx 1 n.s 74.0 Weakly correlated
53 AluSg4 1 n.s 74.0 Weakly correlated
54 AluSg 1 n.s 74.0 Weakly correlated
55 THE1D-int 1 n.s 28.9 Weakly correlated
56 L1M3 1 n.s 99.0 Weakly correlated
57 L1MC4 1 n.s 99.0 Weakly correlated
58 L1PA14 1 n.s 74.0 Weakly correlated
59 L1PA16 1 n.s 74.0 Weakly correlated
60 L1PA17 1 n.s 74.0 Weakly correlated
61 L1MB8 1 n.s 99.0 Weakly correlated
62 L1MB4 1 n.s 99.0 Weakly correlated
63 L1PA4 1 n.s 19.6 Weakly correlated
64 L1MA9 1 n.s 99.0 Weakly correlated
65 L2 1 n.s 99.0 Weakly correlated
66 L2b 1 n.s 99.0 Weakly correlated
67 HAL1 1 n.s 99.0 Weakly correlated
68 LFSINE_Vert 1 * 319.0 Weakly correlated
69 LTR1 1 ** 43.0 Highly correlated
70 L1M2b 1 ** 87.0 Weakly correlated
71 LTR10B1 1 *** 28.9 Weakly correlated
72 L1M2 1 n.s 99.0 Weakly correlated
73 HERVH-int 1 n.s 28.9 Weakly correlated
74 HERVE_a-int 1 * 28.9 Weakly correlated
75 LTR1D 1 ** 43.0 Highly correlated
76 LTR2752 1 ** 43.0 Highly correlated
77 L1MEc 1 n.s 99.0 Weakly correlated
Motif in Repeats The motif of KZFPs identified by the MEME-ChIP is present in repeats sequences. :
# Repeats name Record number Significance Emergence time(Mya) Time correlation with KZFP
1 L1P3 6 ** 74.0 Weakly correlated
2 L1M3 1 n.s 99.0 Weakly correlated
3 LTR46 1 *** 43.0 Highly correlated
4 L1PA2 1 n.s 15.2 Weakly correlated
Motif in Repeats Consensus The motif of KZFPs identified by MEME-ChIP analysis can be utilized to locate the corresponding region within the consensus sequences of repeats. :
# Repeats name Emergence time(Mya) Time correlation with KZFP