Human_ZNF562
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ProteinZinc finger protein 562
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Length426
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OrganismHomo sapiens (Human)
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Time of emergence43.0 Mya
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Time of Changing in binding specificity28.9 Mya
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Uniprot_ID
-
NCBI_ID
Sequence:
MSAFDMSHGFFPREPICPFEEKTKIGTMVEDHRSNSYQDSVTFDDVAVEFTPEEWALLDTTQKYLYRDVMLENYMNLASVDFFFCLTSEWEIQPRTKRSSLQQGFLKNQIFTGIQMQTRSYSGWKLCENCGEVFSEQFCLKTHMRAQNGGNTFEGNCYGKDSISVHKEASIGQELSKFNPCGKVFTLTPGLAVHLEILNGRQPYKCKECGKGFKYFASLDNHMGIHIGEKLCEFQECERAITTSSHLKQCVAVHTGKKSEKTKNCGKSFTNFSQLSAHAKTHKGEKSFECKECGRSFRNSSSFNVHIQIHTGIKPHKCTECGKAFTRSTHLTQHVRTHTGIKPYECKECGQAFTQYTGLAIHIRNHTGEKPYQCKECGKAFNRSSTLTQHRRIHTGEKPYECVECGKTFITSSHRSKHLKTHSGER
Domain
:
| # | Domain name | Pos | |
|---|---|---|---|
| 1 | KRAB | 41..120 | |
| 2 | dec2h2 | 176..198 | |
| 3 | C2h2 | 204..226 | |
| 4 | dec2h2 | 260..282 | |
| 5 | C2h2 | 288..310 | |
| 6 | C2h2 | 316..338 | |
| 7 | C2h2 | 344..366 | |
| 8 | C2h2 | 372..394 | |
| 9 | C2h2 | 400..422 |
Gene Ontology Annotation
:
| # | Type | TERM | |
|---|---|---|---|
| 1 | Cellular Component | nucleus | |
| 2 | Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | |
| 3 | Molecular Function | metal ion binding | |
| 4 | Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | |
| 5 | Biological Process | regulation of DNA-templated transcription |
Is there ChIP-seq data
:
Yes
Motif(meme-ChIP)
:
Forward:
Reverse:
Peak overlapping
:
| # | Repeats name | Record number | Significance | Emergence time(Mya) | Time correlation with KZFP | |
|---|---|---|---|---|---|---|
| 1 | LTR10A | 117 | **** | 28.9 | Highly correlated | |
| 2 | LTR10B1 | 45 | **** | 28.9 | Highly correlated | |
| 3 | LTR10E | 40 | **** | 28.9 | Highly correlated | |
| 4 | LTR10B2 | 32 | **** | 28.9 | Highly correlated | |
| 5 | LTR10F | 23 | **** | 28.9 | Highly correlated | |
| 6 | LTR10G | 22 | **** | 28.9 | Highly correlated | |
| 7 | LTR10B | 18 | **** | 28.9 | Highly correlated | |
| 8 | HERVIP10B3-int | 15 | **** | 28.9 | Highly correlated | |
| 9 | AluSx | 14 | ** | 74.0 | Weakly correlated | |
| 10 | HERVIP10F-int | 8 | **** | 28.9 | Highly correlated | |
| 11 | LTR10C | 7 | **** | 28.9 | Highly correlated | |
| 12 | AluJb | 7 | n.s | 74.0 | Weakly correlated | |
| 13 | HERVIP10FH-int | 6 | **** | 28.9 | Highly correlated | |
| 14 | HERVI-int | 5 | **** | 28.9 | Highly correlated | |
| 15 | L2b | 5 | n.s | 99.0 | Weakly correlated | |
| 16 | AluY | 5 | n.s | 74.0 | Weakly correlated | |
| 17 | MIRb | 4 | n.s | 99.0 | Weakly correlated | |
| 18 | MER51-int | 3 | **** | 43.0 | Moderately correlated | |
| 19 | L2c | 3 | n.s | 99.0 | Weakly correlated | |
| 20 | HAL1 | 3 | n.s | 99.0 | Weakly correlated | |
| 21 | AluSc | 2 | n.s | 74.0 | Weakly correlated | |
| 22 | L1PA2 | 2 | n.s | 15.2 | Weakly correlated | |
| 23 | L1P3 | 2 | * | 74.0 | Weakly correlated | |
| 24 | L1PA5 | 2 | n.s | 19.6 | Weakly correlated | |
| 25 | L1MEc | 2 | n.s | 99.0 | Weakly correlated | |
| 26 | MER4-int | 2 | ** | 74.0 | Weakly correlated | |
| 27 | MER41A | 2 | ** | 74.0 | Weakly correlated | |
| 28 | L2 | 2 | n.s | 99.0 | Weakly correlated | |
| 29 | L2a | 2 | n.s | 99.0 | Weakly correlated | |
| 30 | HUERS-P3b-int | 2 | *** | 43.0 | Moderately correlated | |
| 31 | MIR3 | 2 | n.s | 99.0 | Weakly correlated | |
| 32 | MSTA | 2 | n.s | 43.0 | Moderately correlated | |
| 33 | AluSx1 | 2 | n.s | 74.0 | Weakly correlated | |
| 34 | AluSz | 2 | n.s | 74.0 | Weakly correlated | |
| 35 | LTR12C | 1 | n.s | 19.6 | Weakly correlated | |
| 36 | MER50-int | 1 | ** | 43.0 | Moderately correlated | |
| 37 | LTR13 | 1 | ** | 19.6 | Weakly correlated | |
| 38 | LTR16A | 1 | * | 99.0 | Weakly correlated | |
| 39 | LTR16C | 1 | n.s | 99.0 | Weakly correlated | |
| 40 | MLT1D | 1 | n.s | 99.0 | Weakly correlated | |
| 41 | SVA_C | 1 | ** | 15.2 | Weakly correlated | |
| 42 | SVA_B | 1 | ** | 15.2 | Weakly correlated | |
| 43 | MSTC | 1 | * | 74.0 | Weakly correlated | |
| 44 | MSTA-int | 1 | n.s | 43.0 | Moderately correlated | |
| 45 | MLT2D | 1 | * | 99.0 | Weakly correlated | |
| 46 | MLT2B2 | 1 | * | 99.0 | Weakly correlated | |
| 47 | MLT1M | 1 | ** | 99.0 | Weakly correlated | |
| 48 | MLT1K | 1 | n.s | 99.0 | Weakly correlated | |
| 49 | LTR19A | 1 | *** | 43.0 | Moderately correlated | |
| 50 | MIRc | 1 | n.s | 99.0 | Weakly correlated | |
| 51 | MER66B | 1 | ** | 43.0 | Moderately correlated | |
| 52 | MER61D | 1 | *** | 43.0 | Moderately correlated | |
| 53 | L1PBa | 1 | n.s | 74.0 | Weakly correlated | |
| 54 | MER50 | 1 | * | 43.0 | Moderately correlated | |
| 55 | MER39B | 1 | ** | 74.0 | Weakly correlated | |
| 56 | MER21C | 1 | n.s | 99.0 | Weakly correlated | |
| 57 | LTR22B1 | 1 | *** | 28.9 | Highly correlated | |
| 58 | L1MA3 | 1 | n.s | 74.0 | Weakly correlated | |
| 59 | AluJo | 1 | n.s | 74.0 | Weakly correlated | |
| 60 | AluJr | 1 | n.s | 74.0 | Weakly correlated | |
| 61 | AluSc5 | 1 | n.s | 74.0 | Weakly correlated | |
| 62 | AluSq | 1 | n.s | 74.0 | Weakly correlated | |
| 63 | AluSq2 | 1 | n.s | 74.0 | Weakly correlated | |
| 64 | AluSx3 | 1 | n.s | 74.0 | Weakly correlated | |
| 65 | AluSz6 | 1 | n.s | 74.0 | Weakly correlated | |
| 66 | AluYh3 | 1 | ** | 15.2 | Weakly correlated | |
| 67 | AluYk3 | 1 | ** | 19.6 | Weakly correlated | |
| 68 | AmnSINE1 | 1 | ** | 319.0 | Weakly correlated | |
| 69 | CR1_Mam | 1 | ** | 99.0 | Weakly correlated | |
| 70 | ERV3-16A3_LTR | 1 | ** | 99.0 | Weakly correlated | |
| 71 | HUERS-P3-int | 1 | ** | 43.0 | Moderately correlated | |
| 72 | L1M1 | 1 | n.s | 74.0 | Weakly correlated | |
| 73 | LTR104_Mam | 1 | ** | 99.0 | Weakly correlated | |
| 74 | L1MA8 | 1 | n.s | 87.0 | Weakly correlated | |
| 75 | L1MB4 | 1 | n.s | 99.0 | Weakly correlated | |
| 76 | L1MC5 | 1 | n.s | 99.0 | Weakly correlated | |
| 77 | L1MDa | 1 | n.s | 99.0 | Weakly correlated | |
| 78 | L1ME2 | 1 | n.s | 99.0 | Weakly correlated | |
| 79 | L1ME4a | 1 | n.s | 99.0 | Weakly correlated | |
| 80 | L1P1 | 1 | n.s | 19.6 | Weakly correlated | |
| 81 | L1P4 | 1 | n.s | 74.0 | Weakly correlated | |
| 82 | L1PA16 | 1 | n.s | 74.0 | Weakly correlated | |
| 83 | L1PA3 | 1 | n.s | 19.6 | Weakly correlated | |
| 84 | L1PA4 | 1 | n.s | 19.6 | Weakly correlated | |
| 85 | L1PB1 | 1 | n.s | 74.0 | Weakly correlated | |
| 86 | L1PREC2 | 1 | n.s | 43.0 | Moderately correlated | |
| 87 | L3 | 1 | n.s | 99.0 | Weakly correlated |
Motif in Repeats
:
| # | Repeats name | Record number | Significance | Emergence time(Mya) | Time correlation with KZFP | |
|---|---|---|---|---|---|---|
| 1 | LTR10A | 109 | **** | 28.9 | Highly correlated | |
| 2 | LTR10B1 | 44 | **** | 28.9 | Highly correlated | |
| 3 | LTR10E | 38 | **** | 28.9 | Highly correlated | |
| 4 | LTR10B2 | 27 | **** | 28.9 | Highly correlated | |
| 5 | LTR10G | 22 | **** | 28.9 | Highly correlated | |
| 6 | LTR10F | 21 | **** | 28.9 | Highly correlated | |
| 7 | LTR10B | 16 | **** | 28.9 | Highly correlated | |
| 8 | LTR10C | 6 | **** | 28.9 | Highly correlated | |
| 9 | HAL1 | 2 | n.s | 99.0 | Weakly correlated | |
| 10 | L2a | 1 | n.s | 99.0 | Weakly correlated | |
| 11 | HERVIP10F-int | 1 | ** | 28.9 | Highly correlated | |
| 12 | AmnSINE1 | 1 | ** | 319.0 | Weakly correlated | |
| 13 | L1PA5 | 1 | n.s | 19.6 | Weakly correlated |
Motif in Repeats Consensus
:
| # | Repeats name | Emergence time(Mya) | Time correlation with KZFP | |
|---|---|---|---|---|
| 1 | LTR10A | 28.9 | Highly correlated | |
| 2 | LTR10B | 28.9 | Highly correlated | |
| 3 | LTR10B1 | 28.9 | Highly correlated | |
| 4 | LTR10B2 | 28.9 | Highly correlated | |
| 5 | LTR10C | 28.9 | Highly correlated | |
| 6 | LTR10E | 28.9 | Highly correlated | |
| 7 | LTR10F | 28.9 | Highly correlated | |
| 8 | LTR10G | 28.9 | Highly correlated |