ZRdb KZFP & Repeats
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Human_ZNF208

  • Protein
    Zinc finger protein 208
  • Length
    1280
  • Organism
    Homo sapiens (Human)
  • Time of emergence
    28.9 Mya
  • Time of Changing in binding specificity
    6.4 Mya
  • Uniprot_ID
    O43345
  • NCBI_ID
    7757
Sequence:
MGSLTFRDVAIEFSLEEWQCLDTAQQNLYRNVMLENYRNLVFLGIAAFKPDLIIFLEEGKESWNMKRHEMVEESPVICSHFAQDLWPEQGIEDSFQKVILRRYEKCGHENLHLKIGYTNVDECKVHKEGYNKLNQSLTTTQSKVFQRGKYANVFHKCSNSNRHKIRHTGKKHLQCKEYVRSFCMLSHLSQHKRIYTRENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPYRCKECGKAFSKFSILTKHKVIHTGEKSYKCEECGKAFNQSAILTKHKIIHTGEKPNKCEECGKAFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKVSTLITHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECGKGFSMFSILTKHKVIHNGEKPYKCEECDKATHAGEKPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNQSAILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKTFIKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFSTFSVLTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIKHKRIHTDEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFSWLSVFSKHKKTHAGEKFYKCEACGKAYKSSSTLSYHKKIHTEEKPYKYEECGKGFSTFSILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECDKAFSWPSSLTEHKATHAGEKPYKCEECGKAFSWPSRLTEHKATHAGEEPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKGFVMFSILAKHKVIHTGEKLYKCEECGKAYKWPSTLRYHKKIHTGEKPYKCEECGKAFSTFSILTKHKVIHTGEKPYKCEECGKAFSWLSVFSKHKKIHTGEKL
Domain KRAB, ZF, and degenerated ZF domains of KZFPs. :
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# Domain name Pos
1 KRAB 4..75
2 dec2h2 173..195
3 dec2h2 201..223
4 C2h2 229..251
5 C2h2 257..279
6 C2h2 285..307
7 C2h2 313..335
8 C2h2 341..363
9 C2h2 369..391
10 C2h2 397..419
11 C2h2 425..447
12 C2h2 453..475
13 C2h2 497..519
14 C2h2 525..547
15 C2h2 553..575
16 C2h2 581..603
17 C2h2 609..631
18 C2h2 637..659
19 C2h2 665..687
20 C2h2 693..715
21 C2h2 721..743
22 C2h2 749..771
23 C2h2 777..799
24 C2h2 805..827
25 C2h2 833..855
26 C2h2 861..883
27 C2h2 889..911
28 C2h2 917..939
29 C2h2 945..967
30 dec2h2 973..995
31 C2h2 1001..1023
32 C2h2 1029..1051
33 C2h2 1057..1079
34 C2h2 1085..1107
35 C2h2 1113..1135
36 C2h2 1141..1163
37 C2h2 1169..1191
38 C2h2 1197..1219
39 C2h2 1225..1247
40 C2h2 1253..1275
Gene Ontology Annotation The Gene Ontology (GO) describes knowledge of the biological domain based on three aspects: Molecular function, Biological process, and Cellular component. :
# Type TERM
1 Cellular Component nucleus
2 Molecular Function DNA-binding transcription activator activity, RNA polymerase II-specific
3 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding
4 Molecular Function zinc ion binding
5 Biological Process regulation of transcription by RNA polymerase II
Is there ChIP-seq data Is there any ChIP-seq data available for these KZFPs in the Cistrome database? :
No
Motif(Predicted) DNA binding motifs predicted using Zinc Finger Recognition Code. :
Forward:
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No Chip-seq
No Chip-seq
No Chip-seq