Human_ZNF114
-
ProteinZinc finger protein 114
-
Length417
-
OrganismHomo sapiens (Human)
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Time of emergence28.9 Mya
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Time of Changing in binding specificity28.9 Mya
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Uniprot_ID
-
NCBI_ID
Sequence:
MSQDSVTFADVAVNFTKEEWTLLDPAQRNLYRDVMLENSRNLAFIDWATPCKTKDATPQPDILPKRTFPEANRVCLTSISSQHSTLREDWRCPKTEEPHRQGVNNVKPPAVAPEKDESPVSICEDHEMRNHSKPTCRLVPSQGDSIRQCILTRDSSIFKYNPVLNDSQKTHENNEDDGVLGWNIQWVPCGRKTELKSSTWTGSQNTVHHIRDEIDTGANRHQRNPFGKAFREDGSLRAHNTHGREKMYDFTQCENTSRNNSIHAMQMQLYTAETNKKDCQTGATSANAPNSGSHKSHCTGEKTHKCPECGRAFFYQSFLMRHMKIHTGEKPYECGKCGKAFRYSLHLNKHLRKHVVQKKPYECEECGKVIRESSKYTHIRSHTGEKPYKCKTCGKDFAKSSGLKKHLKTHKDEKPCE
Domain
:
| # | Domain name | Pos | |
|---|---|---|---|
| 1 | KRAB | 6..85 | |
| 2 | C2h2 | 304..326 | |
| 3 | C2h2 | 332..354 | |
| 4 | C2h2 | 361..382 | |
| 5 | C2h2 | 388..410 |
Gene Ontology Annotation
:
| # | Type | TERM | |
|---|---|---|---|
| 1 | Cellular Component | extracellular exosome | |
| 2 | Cellular Component | nucleus | |
| 3 | Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | |
| 4 | Molecular Function | identical protein binding | |
| 5 | Molecular Function | metal ion binding | |
| 6 | Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | |
| 7 | Biological Process | regulation of DNA-templated transcription |
Is there ChIP-seq data
:
Yes
Motif(meme-ChIP)
:
Forward:
Reverse:
Peak overlapping
:
| # | Repeats name | Record number | Significance | Emergence time(Mya) | Time correlation with KZFP | |
|---|---|---|---|---|---|---|
| 1 | MER52A | 59 | **** | 74.0 | Weakly correlated | |
| 2 | LTR12C | 44 | **** | 19.6 | Weakly correlated | |
| 3 | MER52D | 21 | **** | 74.0 | Weakly correlated | |
| 4 | L1PA13 | 14 | *** | 74.0 | Weakly correlated | |
| 5 | L2a | 12 | n.s | 99.0 | Weakly correlated | |
| 6 | L2c | 11 | n.s | 99.0 | Weakly correlated | |
| 7 | AluJb | 10 | n.s | 74.0 | Weakly correlated | |
| 8 | L1PA10 | 10 | * | 74.0 | Weakly correlated | |
| 9 | L2b | 10 | n.s | 99.0 | Weakly correlated | |
| 10 | AluSc8 | 8 | * | 74.0 | Weakly correlated | |
| 11 | L1PA15 | 8 | n.s | 74.0 | Weakly correlated | |
| 12 | LTR12E | 8 | **** | 19.6 | Weakly correlated | |
| 13 | MER50 | 8 | **** | 43.0 | Moderately correlated | |
| 14 | L1MA4A | 7 | * | 87.0 | Weakly correlated | |
| 15 | L1MA8 | 7 | n.s | 87.0 | Weakly correlated | |
| 16 | LTR10A | 7 | **** | 28.9 | Highly correlated | |
| 17 | LTR8 | 7 | **** | 43.0 | Moderately correlated | |
| 18 | MER52C | 7 | **** | 74.0 | Weakly correlated | |
| 19 | L1M2 | 6 | n.s | 99.0 | Weakly correlated | |
| 20 | L1M3e | 6 | **** | 99.0 | Weakly correlated | |
| 21 | MIR | 6 | n.s | 99.0 | Weakly correlated | |
| 22 | L1PA16 | 5 | n.s | 74.0 | Weakly correlated | |
| 23 | L1PB4 | 5 | n.s | 99.0 | Weakly correlated | |
| 24 | L1PREC2 | 5 | n.s | 43.0 | Moderately correlated | |
| 25 | LTR12D | 5 | **** | 19.6 | Weakly correlated | |
| 26 | MIRb | 5 | n.s | 99.0 | Weakly correlated | |
| 27 | THE1D-int | 5 | ** | 28.9 | Highly correlated | |
| 28 | L1M1 | 4 | n.s | 74.0 | Weakly correlated | |
| 29 | L1MEf | 4 | n.s | 99.0 | Weakly correlated | |
| 30 | L1P3 | 4 | n.s | 74.0 | Weakly correlated | |
| 31 | L2 | 4 | n.s | 99.0 | Weakly correlated | |
| 32 | LTR2752 | 4 | **** | 43.0 | Moderately correlated | |
| 33 | MIRc | 4 | n.s | 99.0 | Weakly correlated | |
| 34 | MLT1L | 4 | * | 99.0 | Weakly correlated | |
| 35 | AluSx1 | 3 | n.s | 74.0 | Weakly correlated | |
| 36 | L1M2b | 3 | **** | 87.0 | Weakly correlated | |
| 37 | L1MA4 | 3 | n.s | 87.0 | Weakly correlated | |
| 38 | L1P4a | 3 | ** | 74.0 | Weakly correlated | |
| 39 | L1PA15-16 | 3 | * | 74.0 | Weakly correlated | |
| 40 | L1PA5 | 3 | n.s | 19.6 | Weakly correlated | |
| 41 | L1PB1 | 3 | n.s | 74.0 | Weakly correlated | |
| 42 | LTR1D | 3 | **** | 43.0 | Moderately correlated | |
| 43 | LTR33A | 3 | *** | 99.0 | Weakly correlated | |
| 44 | MSTB-int | 3 | ** | 43.0 | Moderately correlated | |
| 45 | SVA_B | 3 | *** | 15.2 | Weakly correlated | |
| 46 | AluJo | 2 | n.s | 74.0 | Weakly correlated | |
| 47 | AluSx | 2 | n.s | 74.0 | Weakly correlated | |
| 48 | AluYh9 | 2 | **** | 15.2 | Weakly correlated | |
| 49 | FRAM | 2 | * | 74.0 | Weakly correlated | |
| 50 | L1M3a | 2 | ** | 99.0 | Weakly correlated | |
| 51 | L1MA1 | 2 | n.s | 74.0 | Weakly correlated | |
| 52 | L1MA2 | 2 | n.s | 74.0 | Weakly correlated | |
| 53 | L1MA5 | 2 | n.s | 87.0 | Weakly correlated | |
| 54 | L1MA9 | 2 | n.s | 99.0 | Weakly correlated | |
| 55 | L1MB3 | 2 | n.s | 99.0 | Weakly correlated | |
| 56 | L1MCb | 2 | n.s | 99.0 | Weakly correlated | |
| 57 | L1MCc | 2 | n.s | 99.0 | Weakly correlated | |
| 58 | L1MDa | 2 | n.s | 99.0 | Weakly correlated | |
| 59 | L1ME3G | 2 | n.s | 99.0 | Weakly correlated | |
| 60 | L1P4b | 2 | *** | 74.0 | Weakly correlated | |
| 61 | L1PA14 | 2 | n.s | 74.0 | Weakly correlated | |
| 62 | L1PA17 | 2 | n.s | 74.0 | Weakly correlated | |
| 63 | L1PA2 | 2 | n.s | 15.2 | Weakly correlated | |
| 64 | L1PA4 | 2 | n.s | 19.6 | Weakly correlated | |
| 65 | L1PA6 | 2 | n.s | 28.9 | Highly correlated | |
| 66 | L1PA8 | 2 | n.s | 74.0 | Weakly correlated | |
| 67 | L3 | 2 | n.s | 99.0 | Weakly correlated | |
| 68 | LTR1A2 | 2 | ** | 43.0 | Moderately correlated | |
| 69 | LTR27E | 2 | *** | 43.0 | Moderately correlated | |
| 70 | LTR28C | 2 | *** | 43.0 | Moderately correlated | |
| 71 | LTR83 | 2 | *** | 99.0 | Weakly correlated | |
| 72 | MLT1C | 2 | n.s | 94.0 | Weakly correlated | |
| 73 | MSTA | 2 | n.s | 43.0 | Moderately correlated | |
| 74 | MSTA-int | 2 | n.s | 43.0 | Moderately correlated | |
| 75 | MamRTE1 | 2 | n.s | 99.0 | Weakly correlated | |
| 76 | Alu | 1 | * | 74.0 | Weakly correlated | |
| 77 | AluJr4 | 1 | n.s | 74.0 | Weakly correlated | |
| 78 | AluSp | 1 | n.s | 74.0 | Weakly correlated | |
| 79 | AluSz6 | 1 | n.s | 74.0 | Weakly correlated | |
| 80 | AluY | 1 | n.s | 74.0 | Weakly correlated | |
| 81 | AluYj4 | 1 | n.s | 0.0 | Weakly correlated | |
| 82 | AluYm1 | 1 | n.s | 19.6 | Weakly correlated | |
| 83 | HAL1 | 1 | n.s | 99.0 | Weakly correlated | |
| 84 | HERV3-int | 1 | * | 28.9 | Highly correlated | |
| 85 | HERVL18-int | 1 | * | 43.0 | Moderately correlated | |
| 86 | L1M2a | 1 | * | 87.0 | Weakly correlated | |
| 87 | L1M2a1 | 1 | ** | 79.0 | Weakly correlated | |
| 88 | L1M2c | 1 | * | 87.0 | Weakly correlated | |
| 89 | L1M4 | 1 | n.s | 99.0 | Weakly correlated | |
| 90 | L1M4c | 1 | n.s | 99.0 | Weakly correlated | |
| 91 | L1MA10 | 1 | n.s | 99.0 | Weakly correlated | |
| 92 | L1MA7 | 1 | n.s | 87.0 | Weakly correlated | |
| 93 | L1MB8 | 1 | n.s | 99.0 | Weakly correlated | |
| 94 | L1ME4b | 1 | n.s | 99.0 | Weakly correlated | |
| 95 | L1P1 | 1 | n.s | 19.6 | Weakly correlated | |
| 96 | L1P3b | 1 | *** | 43.0 | Moderately correlated | |
| 97 | L1P4 | 1 | n.s | 74.0 | Weakly correlated | |
| 98 | L1P4e | 1 | ** | 74.0 | Weakly correlated | |
| 99 | L1PA11 | 1 | n.s | 74.0 | Weakly correlated | |
| 100 | L1PA12 | 1 | n.s | 74.0 | Weakly correlated | |
| 101 | L1PA8A | 1 | n.s | 74.0 | Weakly correlated | |
| 102 | L1PBa | 1 | n.s | 74.0 | Weakly correlated | |
| 103 | L1PBb | 1 | * | 74.0 | Weakly correlated | |
| 104 | L2-1_AMi | 1 | ** | 319.0 | Weakly correlated | |
| 105 | L4_A_Mam | 1 | n.s | 99.0 | Weakly correlated | |
| 106 | LTR10B1 | 1 | *** | 28.9 | Highly correlated | |
| 107 | LTR13 | 1 | * | 19.6 | Weakly correlated | |
| 108 | LTR13A | 1 | ** | 28.9 | Highly correlated | |
| 109 | LTR16A | 1 | n.s | 99.0 | Weakly correlated | |
| 110 | LTR16B2 | 1 | n.s | 99.0 | Weakly correlated | |
| 111 | LTR16D | 1 | * | 99.0 | Weakly correlated | |
| 112 | LTR16D2 | 1 | ** | 99.0 | Weakly correlated | |
| 113 | LTR16E1 | 1 | n.s | 99.0 | Weakly correlated | |
| 114 | LTR16E2 | 1 | n.s | 99.0 | Weakly correlated | |
| 115 | LTR1C1 | 1 | *** | 43.0 | Moderately correlated | |
| 116 | LTR33 | 1 | n.s | 99.0 | Weakly correlated | |
| 117 | LTR41B | 1 | * | 99.0 | Weakly correlated | |
| 118 | LTR41C | 1 | * | 99.0 | Weakly correlated | |
| 119 | LTR50 | 1 | n.s | 99.0 | Weakly correlated | |
| 120 | LTR51 | 1 | ** | 74.0 | Weakly correlated | |
| 121 | MER39B | 1 | * | 74.0 | Weakly correlated | |
| 122 | MER50-int | 1 | * | 43.0 | Moderately correlated | |
| 123 | MER70C | 1 | ** | 99.0 | Weakly correlated | |
| 124 | MER88 | 1 | *** | 99.0 | Weakly correlated | |
| 125 | MIR3 | 1 | n.s | 99.0 | Weakly correlated | |
| 126 | MLT1A-int | 1 | ** | 99.0 | Weakly correlated | |
| 127 | MLT1A0-int | 1 | n.s | 99.0 | Weakly correlated | |
| 128 | MLT1A1-int | 1 | * | 87.0 | Weakly correlated | |
| 129 | MLT1B | 1 | n.s | 99.0 | Weakly correlated | |
| 130 | MLT1H | 1 | n.s | 99.0 | Weakly correlated | |
| 131 | MLT1H1 | 1 | n.s | 99.0 | Weakly correlated | |
| 132 | MLT1N2 | 1 | n.s | 99.0 | Weakly correlated | |
| 133 | MLT2C1 | 1 | n.s | 99.0 | Weakly correlated | |
| 134 | SVA_C | 1 | * | 15.2 | Weakly correlated | |
| 135 | SVA_E | 1 | * | 0.0 | Weakly correlated | |
| 136 | SVA_F | 1 | n.s | 0.0 | Weakly correlated | |
| 137 | THE1A-int | 1 | n.s | 43.0 | Moderately correlated | |
| 138 | THE1B | 1 | n.s | 43.0 | Moderately correlated | |
| 139 | THE1B-int | 1 | n.s | 43.0 | Moderately correlated | |
| 140 | THE1C-int | 1 | n.s | 43.0 | Moderately correlated | |
| 141 | THE1D | 1 | n.s | 43.0 | Moderately correlated |
Motif in Repeats
:
| # | Repeats name | Record number | Significance | Emergence time(Mya) | Time correlation with KZFP | |
|---|---|---|---|---|---|---|
| 1 | L1MA9 | 2 | n.s | 99.0 | Weakly correlated | |
| 2 | LTR27E | 2 | *** | 43.0 | Moderately correlated | |
| 3 | AluJb | 1 | n.s | 74.0 | Weakly correlated | |
| 4 | AluYh9 | 1 | **** | 15.2 | Weakly correlated | |
| 5 | L1MA2 | 1 | n.s | 74.0 | Weakly correlated | |
| 6 | L1PB4 | 1 | n.s | 99.0 | Weakly correlated | |
| 7 | LTR1C1 | 1 | *** | 43.0 | Moderately correlated | |
| 8 | L1PA8A | 1 | n.s | 74.0 | Weakly correlated | |
| 9 | L2b | 1 | n.s | 99.0 | Weakly correlated | |
| 10 | L1PA17 | 1 | n.s | 74.0 | Weakly correlated | |
| 11 | L4_A_Mam | 1 | n.s | 99.0 | Weakly correlated | |
| 12 | L1PA11 | 1 | n.s | 74.0 | Weakly correlated | |
| 13 | LTR13 | 1 | * | 19.6 | Weakly correlated | |
| 14 | MER52A | 1 | n.s | 74.0 | Weakly correlated | |
| 15 | L1PA5 | 1 | n.s | 19.6 | Weakly correlated |
Motif in Repeats Consensus
:
| # | Repeats name | Emergence time(Mya) | Time correlation with KZFP |
|---|