Human_ZFP90
-
ProteinZinc finger protein 90 homolog
-
Length636
-
OrganismHomo sapiens (Human)
-
Time of emergence99.0 Mya
-
Time of Changing in binding specificity99.0 Mya
-
Uniprot_ID
-
NCBI_ID
Sequence:
MAPRPPTAAPQESVTFKDVSVDFTQEEWYHVDPAQRSLYRDVMLENYSHLVSLGYQVSKPEVIFKLEQGEEPWISEGEIQRPFYPDWKTRPEVKSSHLQQDVSEVSHCTHDLLHATLEDSWDVSSQLDRQQENWKRHLGSEASTQKKIITPQENFEQNKFGENSRLNTNLVTQLNIPARIRPSECETLGSNLGHNADLLNENNILAKKKPYKCDKCRKAFIHRSSLTKHEKTHKGEGAFPNGTDQGIYPGKKHHECTDCGKTFLWKTQLTEHQRIHTGEKPFECNVCGKAFRHSSSLGQHENAHTGEKPYQCSLCGKAFQRSSSLVQHQRIHTGEKPYRCNLCGRSFRHGTSLTQHEVTHSGEKPFQCKECGKAFSRCSSLVQHERTHTGEKPFECSICGRAFGQSPSLYKHMRIHKRGKPYQSSNYSIDFKHSTSLTQDESTLTEVKSYHCNDCGEDFSHITDFTDHQRIHTAENPYDCEQAFSQQAISHPGEKPYQCNVCGKAFKRSTSFIEHHRIHTGEKPYECNECGEAFSRRSSLTQHERTHTGEKPYECIDCGKAFSQSSSLIQHERTHTGEKPYECNECGRAFRKKTNLHDHQRIHTGEKPYSCKECGKNFSRSSALTKHQRIHTRNKL
Domain
:
| # | Domain name | Pos | |
|---|---|---|---|
| 1 | KRAB | 14..85 | |
| 2 | C2h2 | 211..233 | |
| 3 | C2h2 | 254..276 | |
| 4 | C2h2 | 282..304 | |
| 5 | C2h2 | 310..332 | |
| 6 | C2h2 | 338..360 | |
| 7 | C2h2 | 366..388 | |
| 8 | C2h2 | 394..416 | |
| 9 | C2h2 | 450..472 | |
| 10 | C2h2 | 497..519 | |
| 11 | C2h2 | 525..547 | |
| 12 | C2h2 | 553..575 | |
| 13 | C2h2 | 581..603 | |
| 14 | C2h2 | 609..631 |
Gene Ontology Annotation
:
| # | Type | TERM | |
|---|---|---|---|
| 1 | Cellular Component | nucleus | |
| 2 | Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | |
| 3 | Molecular Function | DNA-binding transcription repressor activity, RNA polymerase II-specific | |
| 4 | Molecular Function | metal ion binding | |
| 5 | Molecular Function | RNA polymerase II transcription regulatory region sequence-specific DNA binding | |
| 6 | Biological Process | negative regulation of DNA binding | |
| 7 | Biological Process | negative regulation of transcription by RNA polymerase II | |
| 8 | Biological Process | positive regulation of DNA-templated transcription | |
| 9 | Biological Process | regulation of transcription by RNA polymerase II |
Is there ChIP-seq data
:
Yes
Motif(meme-ChIP)
:
Forward:
Reverse:
Peak overlapping
:
| # | Repeats name | Record number | Significance | Emergence time(Mya) | Time correlation with KZFP | |
|---|---|---|---|---|---|---|
| 1 | L1PA7 | 45 | **** | 74.0 | Weakly correlated | |
| 2 | L1M5 | 36 | **** | 99.0 | Highly correlated | |
| 3 | L1PB1 | 30 | **** | 74.0 | Weakly correlated | |
| 4 | L1PA8 | 24 | **** | 74.0 | Weakly correlated | |
| 5 | L1MEc | 17 | **** | 99.0 | Highly correlated | |
| 6 | L1PA14 | 16 | **** | 74.0 | Weakly correlated | |
| 7 | L1PREC2 | 16 | **** | 43.0 | Weakly correlated | |
| 8 | L1M4 | 14 | **** | 99.0 | Highly correlated | |
| 9 | L1PA10 | 14 | **** | 74.0 | Weakly correlated | |
| 10 | L1ME1 | 13 | ** | 99.0 | Highly correlated | |
| 11 | L1MD | 12 | **** | 99.0 | Highly correlated | |
| 12 | L1MEf | 11 | **** | 99.0 | Highly correlated | |
| 13 | L1P3 | 11 | **** | 74.0 | Weakly correlated | |
| 14 | AluJb | 10 | n.s | 74.0 | Weakly correlated | |
| 15 | AluJr | 10 | n.s | 74.0 | Weakly correlated | |
| 16 | L1PA13 | 10 | *** | 74.0 | Weakly correlated | |
| 17 | L1MDa | 9 | **** | 99.0 | Highly correlated | |
| 18 | FRAM | 8 | **** | 74.0 | Weakly correlated | |
| 19 | L1MD1 | 8 | **** | 99.0 | Highly correlated | |
| 20 | L1MD2 | 8 | *** | 99.0 | Highly correlated | |
| 21 | AluJo | 7 | n.s | 74.0 | Weakly correlated | |
| 22 | L1MC | 7 | **** | 99.0 | Highly correlated | |
| 23 | L1MCa | 7 | *** | 99.0 | Highly correlated | |
| 24 | L1PA11 | 7 | *** | 74.0 | Weakly correlated | |
| 25 | L1PA8A | 7 | **** | 74.0 | Weakly correlated | |
| 26 | L1M1 | 5 | n.s | 74.0 | Weakly correlated | |
| 27 | L1MB4 | 5 | ** | 99.0 | Highly correlated | |
| 28 | L1MEd | 5 | * | 99.0 | Highly correlated | |
| 29 | L1P2 | 5 | *** | 28.9 | Weakly correlated | |
| 30 | L1PA12 | 5 | **** | 74.0 | Weakly correlated | |
| 31 | L1PA5 | 5 | n.s | 19.6 | Weakly correlated | |
| 32 | AluSz | 4 | n.s | 74.0 | Weakly correlated | |
| 33 | AluY | 4 | n.s | 74.0 | Weakly correlated | |
| 34 | AluYj4 | 4 | **** | 0.0 | Weakly correlated | |
| 35 | L1M4b | 4 | ** | 99.0 | Highly correlated | |
| 36 | L1M4c | 4 | *** | 99.0 | Highly correlated | |
| 37 | L1MA1 | 4 | * | 74.0 | Weakly correlated | |
| 38 | L1PA16 | 4 | n.s | 74.0 | Weakly correlated | |
| 39 | L2a | 4 | n.s | 99.0 | Highly correlated | |
| 40 | AluJr4 | 3 | n.s | 74.0 | Weakly correlated | |
| 41 | AluSx | 3 | n.s | 74.0 | Weakly correlated | |
| 42 | L1M3 | 3 | * | 99.0 | Highly correlated | |
| 43 | L1MA2 | 3 | n.s | 74.0 | Weakly correlated | |
| 44 | L1MA8 | 3 | n.s | 87.0 | Weakly correlated | |
| 45 | L1MB1 | 3 | * | 99.0 | Highly correlated | |
| 46 | L1MB5 | 3 | n.s | 99.0 | Highly correlated | |
| 47 | L1MB8 | 3 | n.s | 99.0 | Highly correlated | |
| 48 | L1MC1 | 3 | n.s | 99.0 | Highly correlated | |
| 49 | L1MC4 | 3 | n.s | 99.0 | Highly correlated | |
| 50 | L1MCc | 3 | ** | 99.0 | Highly correlated | |
| 51 | L1ME3Cz | 3 | * | 99.0 | Highly correlated | |
| 52 | L1ME4b | 3 | n.s | 99.0 | Highly correlated | |
| 53 | L1MEg | 3 | n.s | 99.0 | Highly correlated | |
| 54 | L1P1 | 3 | * | 19.6 | Weakly correlated | |
| 55 | L1P4 | 3 | ** | 74.0 | Weakly correlated | |
| 56 | L1PA2 | 3 | n.s | 15.2 | Weakly correlated | |
| 57 | L1PA3 | 3 | n.s | 19.6 | Weakly correlated | |
| 58 | L1PB2 | 3 | ** | 74.0 | Weakly correlated | |
| 59 | LTR10A | 3 | **** | 28.9 | Weakly correlated | |
| 60 | MIRb | 3 | n.s | 99.0 | Highly correlated | |
| 61 | AluSz6 | 2 | n.s | 74.0 | Weakly correlated | |
| 62 | L1M4a2 | 2 | ** | 99.0 | Highly correlated | |
| 63 | L1MA7 | 2 | n.s | 87.0 | Weakly correlated | |
| 64 | L1MC2 | 2 | n.s | 99.0 | Highly correlated | |
| 65 | L1MC3 | 2 | n.s | 99.0 | Highly correlated | |
| 66 | L1ME3G | 2 | n.s | 99.0 | Highly correlated | |
| 67 | L1PA6 | 2 | n.s | 28.9 | Weakly correlated | |
| 68 | L1PB3 | 2 | n.s | 74.0 | Weakly correlated | |
| 69 | L1PBa | 2 | n.s | 74.0 | Weakly correlated | |
| 70 | L1PBa1 | 2 | ** | 74.0 | Weakly correlated | |
| 71 | MIR3 | 2 | n.s | 99.0 | Highly correlated | |
| 72 | AluSg | 1 | n.s | 74.0 | Weakly correlated | |
| 73 | AluSq2 | 1 | n.s | 74.0 | Weakly correlated | |
| 74 | AluSx1 | 1 | n.s | 74.0 | Weakly correlated | |
| 75 | AluYa5 | 1 | n.s | 15.2 | Weakly correlated | |
| 76 | AluYf1 | 1 | * | 19.6 | Weakly correlated | |
| 77 | AluYh9 | 1 | **** | 15.2 | Weakly correlated | |
| 78 | AluYm1 | 1 | n.s | 19.6 | Weakly correlated | |
| 79 | FAM | 1 | * | 87.0 | Weakly correlated | |
| 80 | FLAM_A | 1 | n.s | 74.0 | Weakly correlated | |
| 81 | FLAM_C | 1 | n.s | 74.0 | Weakly correlated | |
| 82 | HAL1 | 1 | n.s | 99.0 | Highly correlated | |
| 83 | L1M2 | 1 | n.s | 99.0 | Highly correlated | |
| 84 | L1M2c | 1 | ** | 87.0 | Weakly correlated | |
| 85 | L1M3c | 1 | * | 99.0 | Highly correlated | |
| 86 | L1MA3 | 1 | n.s | 74.0 | Weakly correlated | |
| 87 | L1MA4 | 1 | n.s | 87.0 | Weakly correlated | |
| 88 | L1MA5A | 1 | n.s | 87.0 | Weakly correlated | |
| 89 | L1MA9 | 1 | n.s | 99.0 | Highly correlated | |
| 90 | L1MDb | 1 | * | 99.0 | Highly correlated | |
| 91 | L1ME3E | 1 | n.s | 99.0 | Highly correlated | |
| 92 | L1ME4a | 1 | n.s | 99.0 | Highly correlated | |
| 93 | L1ME5 | 1 | * | 99.0 | Highly correlated | |
| 94 | L1P4a | 1 | * | 74.0 | Weakly correlated | |
| 95 | L1PA15 | 1 | n.s | 74.0 | Weakly correlated | |
| 96 | L1PA15-16 | 1 | n.s | 74.0 | Weakly correlated | |
| 97 | L1PA17 | 1 | n.s | 74.0 | Weakly correlated | |
| 98 | L2b | 1 | n.s | 99.0 | Highly correlated | |
| 99 | L2c | 1 | n.s | 99.0 | Highly correlated | |
| 100 | L3 | 1 | n.s | 99.0 | Highly correlated | |
| 101 | LTR10F | 1 | ** | 28.9 | Weakly correlated | |
| 102 | LTR13 | 1 | * | 19.6 | Weakly correlated | |
| 103 | LTR16 | 1 | * | 99.0 | Highly correlated | |
| 104 | LTR16A | 1 | n.s | 99.0 | Highly correlated | |
| 105 | MER34C2 | 1 | ** | 74.0 | Weakly correlated | |
| 106 | MER39B | 1 | * | 74.0 | Weakly correlated | |
| 107 | MER50 | 1 | n.s | 43.0 | Weakly correlated | |
| 108 | MER50-int | 1 | ** | 43.0 | Weakly correlated | |
| 109 | MIR | 1 | n.s | 99.0 | Highly correlated | |
| 110 | MLT1A1 | 1 | n.s | 87.0 | Weakly correlated | |
| 111 | MLT1F1 | 1 | * | 99.0 | Highly correlated | |
| 112 | MLT1K | 1 | n.s | 99.0 | Highly correlated | |
| 113 | MSTA | 1 | n.s | 43.0 | Weakly correlated | |
| 114 | MamRTE1 | 1 | n.s | 99.0 | Highly correlated | |
| 115 | MamRep605 | 1 | * | 99.0 | Highly correlated | |
| 116 | PRIMA41-int | 1 | ** | 74.0 | Weakly correlated |
Motif in Repeats
:
| # | Repeats name | Record number | Significance | Emergence time(Mya) | Time correlation with KZFP | |
|---|---|---|---|---|---|---|
| 1 | L1PA7 | 44 | **** | 74.0 | Weakly correlated | |
| 2 | L1M5 | 31 | **** | 99.0 | Highly correlated | |
| 3 | L1PB1 | 29 | **** | 74.0 | Weakly correlated | |
| 4 | L1PA8 | 22 | **** | 74.0 | Weakly correlated | |
| 5 | L1PREC2 | 16 | **** | 43.0 | Weakly correlated | |
| 6 | L1PA14 | 14 | **** | 74.0 | Weakly correlated | |
| 7 | L1M4 | 13 | **** | 99.0 | Highly correlated | |
| 8 | L1MEc | 13 | **** | 99.0 | Highly correlated | |
| 9 | L1PA10 | 12 | **** | 74.0 | Weakly correlated | |
| 10 | L1MEf | 10 | **** | 99.0 | Highly correlated | |
| 11 | L1ME1 | 10 | * | 99.0 | Highly correlated | |
| 12 | L1MD | 10 | **** | 99.0 | Highly correlated | |
| 13 | L1PA13 | 9 | *** | 74.0 | Weakly correlated | |
| 14 | AluJr | 8 | n.s | 74.0 | Weakly correlated | |
| 15 | L1MD1 | 8 | **** | 99.0 | Highly correlated | |
| 16 | L1PA8A | 7 | **** | 74.0 | Weakly correlated | |
| 17 | L1P3 | 7 | **** | 74.0 | Weakly correlated | |
| 18 | L1MDa | 7 | *** | 99.0 | Highly correlated | |
| 19 | L1MCa | 7 | *** | 99.0 | Highly correlated | |
| 20 | FRAM | 6 | **** | 74.0 | Weakly correlated | |
| 21 | L1PA11 | 6 | *** | 74.0 | Weakly correlated | |
| 22 | L1P2 | 6 | **** | 28.9 | Weakly correlated | |
| 23 | L1MC | 6 | **** | 99.0 | Highly correlated | |
| 24 | L1MD2 | 6 | ** | 99.0 | Highly correlated | |
| 25 | AluJo | 5 | n.s | 74.0 | Weakly correlated | |
| 26 | L1PA12 | 5 | **** | 74.0 | Weakly correlated | |
| 27 | L1MEd | 4 | n.s | 99.0 | Highly correlated | |
| 28 | L1M1 | 4 | n.s | 74.0 | Weakly correlated | |
| 29 | L1M4b | 4 | ** | 99.0 | Highly correlated | |
| 30 | L1MA1 | 4 | * | 74.0 | Weakly correlated | |
| 31 | L1MB1 | 4 | ** | 99.0 | Highly correlated | |
| 32 | L1PA16 | 3 | n.s | 74.0 | Weakly correlated | |
| 33 | L1MB4 | 3 | * | 99.0 | Highly correlated | |
| 34 | L1MEg | 3 | n.s | 99.0 | Highly correlated | |
| 35 | L1MA2 | 3 | n.s | 74.0 | Weakly correlated | |
| 36 | L1PB2 | 3 | ** | 74.0 | Weakly correlated | |
| 37 | L1MB5 | 3 | n.s | 99.0 | Highly correlated | |
| 38 | L1PBa1 | 3 | *** | 74.0 | Weakly correlated | |
| 39 | L1MB8 | 3 | n.s | 99.0 | Highly correlated | |
| 40 | L1MC1 | 3 | n.s | 99.0 | Highly correlated | |
| 41 | L1M4c | 3 | ** | 99.0 | Highly correlated | |
| 42 | L1PA3 | 3 | n.s | 19.6 | Weakly correlated | |
| 43 | L1MCc | 3 | ** | 99.0 | Highly correlated | |
| 44 | L1PA6 | 2 | n.s | 28.9 | Weakly correlated | |
| 45 | L1MA8 | 2 | n.s | 87.0 | Weakly correlated | |
| 46 | L1M3 | 2 | n.s | 99.0 | Highly correlated | |
| 47 | L1P4 | 2 | * | 74.0 | Weakly correlated | |
| 48 | L1MC4 | 2 | n.s | 99.0 | Highly correlated | |
| 49 | AluJr4 | 2 | n.s | 74.0 | Weakly correlated | |
| 50 | L1ME4b | 2 | n.s | 99.0 | Highly correlated | |
| 51 | L1PB3 | 2 | n.s | 74.0 | Weakly correlated | |
| 52 | L1ME3G | 2 | n.s | 99.0 | Highly correlated | |
| 53 | L1PBa | 2 | n.s | 74.0 | Weakly correlated | |
| 54 | L1MC2 | 2 | n.s | 99.0 | Highly correlated | |
| 55 | L1MA4 | 1 | n.s | 87.0 | Weakly correlated | |
| 56 | L1MA5A | 1 | n.s | 87.0 | Weakly correlated | |
| 57 | L1MA7 | 1 | n.s | 87.0 | Weakly correlated | |
| 58 | L1PA5 | 1 | n.s | 19.6 | Weakly correlated | |
| 59 | L1MA3 | 1 | n.s | 74.0 | Weakly correlated | |
| 60 | L1PA2 | 1 | n.s | 15.2 | Weakly correlated | |
| 61 | L1PA17 | 1 | n.s | 74.0 | Weakly correlated | |
| 62 | L1PA15-16 | 1 | n.s | 74.0 | Weakly correlated | |
| 63 | L1PA15 | 1 | n.s | 74.0 | Weakly correlated | |
| 64 | L1M2 | 1 | n.s | 99.0 | Highly correlated | |
| 65 | L1M2c | 1 | ** | 87.0 | Weakly correlated | |
| 66 | L1MA9 | 1 | n.s | 99.0 | Highly correlated | |
| 67 | L1P1 | 1 | n.s | 19.6 | Weakly correlated | |
| 68 | L1M3c | 1 | * | 99.0 | Highly correlated | |
| 69 | L1M4a2 | 1 | * | 99.0 | Highly correlated | |
| 70 | L1ME4a | 1 | n.s | 99.0 | Highly correlated | |
| 71 | L1ME3E | 1 | n.s | 99.0 | Highly correlated | |
| 72 | L1MDb | 1 | * | 99.0 | Highly correlated | |
| 73 | L1MC3 | 1 | n.s | 99.0 | Highly correlated |