ZRdb KZFP & Repeats
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Human_ZFP82

  • Protein
    Zinc finger protein 82 homolog
  • Length
    532
  • Organism
    Homo sapiens (Human)
  • Time of emergence
    99.0 Mya
  • Time of Changing in binding specificity
    99.0 Mya
  • Uniprot_ID
    Q8N141
  • NCBI_ID
    284406
Sequence:
MALRSVMFSDVSIDFSPEEWEYLDLEQKDLYRDVMLENYSNLVSLGCFISKPDVISSLEQGKEPWKVVRKGRRQYPDLETKYETKKLSLENDIYEINLSQWKIMERIENHGLKGLILKNDWESTGKIEGQERPQEGYFSSVKMPSEKVSSYQKRTSVTPHQRLHFVDKPYECKECGKAFRVRQQLTFHHRIHTGEKPYECKECGMAFRQTAHLTRHQRLHSGEKLYECKECGEAFICGADLRVHQKMHIGEKPYECKECGKAFRVRGQLTLHQRIHTGEKPYVCKECGKAFRQYAHLTRHQKLNSADRLYECKECGKAFLCGSGLRVHHKLHTGEKPYECKECGKAFRVRQQLTLHQRIHTGEKPYECKECGKTFSRGYHLILHHRIHTGEKPYECKECWKAFSRYSQLISHQSIHIGVKPYDCKECGKAFRLLSQLTQHQSIHIGEKPYKCKECGKAFRLRQKLTLHQSIHTGEKPFECKECRKAFRLNSSLIQHLRIHSGEKPYECKECKKAFRQHSHLTHHLKIHNVKI
Domain KRAB, ZF, and degenerated ZF domains of KZFPs. :
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# Domain name Pos
1 KRAB 6..77
2 C2h2 170..192
3 C2h2 198..220
4 C2h2 226..248
5 C2h2 254..276
6 dec2h2 282..304
7 C2h2 310..332
8 C2h2 338..360
9 C2h2 366..388
10 C2h2 394..416
11 C2h2 422..444
12 C2h2 450..472
13 C2h2 478..500
14 C2h2 506..528
Gene Ontology Annotation The Gene Ontology (GO) describes knowledge of the biological domain based on three aspects: Molecular function, Biological process, and Cellular component. :
# Type TERM
1 Cellular Component nucleus
2 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific
3 Molecular Function metal ion binding
4 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding
5 Biological Process regulation of transcription by RNA polymerase II
Is there ChIP-seq data Is there any ChIP-seq data available for these KZFPs in the Cistrome database? :
Yes
Motif(meme-ChIP) DNA binding motifs of KZFPs obtained using meme-ChIP and mapped using pylogo. :
Forward:
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Reverse:
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Peak overlapping A ChIP-seq peak of KZFPs that intersects with a certain repeats sequences on the genome. :
# Repeats name Record number Significance Emergence time(Mya) Time correlation with KZFP
1 L1MEd 164 **** 99.0 Highly correlated
2 L1MEg 81 **** 99.0 Highly correlated
3 L1MEi 18 **** 99.0 Highly correlated
4 L1ME3B 9 **** 99.0 Highly correlated
5 L1ME3A 8 **** 99.0 Highly correlated
6 L1MCa 7 **** 99.0 Highly correlated
7 L1ME4a 6 ** 99.0 Highly correlated
8 L2a 6 n.s 99.0 Highly correlated
9 L1ME3F 5 **** 99.0 Highly correlated
10 AluSx1 5 n.s 74.0 Weakly correlated
11 L1M1 4 * 74.0 Weakly correlated
12 L1MB7 4 n.s 99.0 Highly correlated
13 L1MEh 4 **** 99.0 Highly correlated
14 AluJr 4 n.s 74.0 Weakly correlated
15 AluSc8 4 * 74.0 Weakly correlated
16 AluSz 3 n.s 74.0 Weakly correlated
17 FLAM_C 3 ** 74.0 Weakly correlated
18 L2c 3 n.s 99.0 Highly correlated
19 HAL1ME 3 ** 99.0 Highly correlated
20 L1ME3Cz 3 ** 99.0 Highly correlated
21 L1M2 3 * 99.0 Highly correlated
22 AluSx 3 n.s 74.0 Weakly correlated
23 L1ME1 3 n.s 99.0 Highly correlated
24 L1M4 3 n.s 99.0 Highly correlated
25 L1ME3 3 ** 99.0 Highly correlated
26 AluY 3 n.s 74.0 Weakly correlated
27 L1ME3E 3 *** 99.0 Highly correlated
28 MIR3 2 n.s 99.0 Highly correlated
29 L1ME3G 2 n.s 99.0 Highly correlated
30 L1ME2 2 n.s 99.0 Highly correlated
31 L1MDa 2 n.s 99.0 Highly correlated
32 MIRc 2 n.s 99.0 Highly correlated
33 MIR 2 n.s 99.0 Highly correlated
34 L1ME3D 2 ** 99.0 Highly correlated
35 LTR16C 2 ** 99.0 Highly correlated
36 L1MEc 2 n.s 99.0 Highly correlated
37 LTR10A 2 **** 28.9 Weakly correlated
38 AluJo 2 n.s 74.0 Weakly correlated
39 L1PA7 2 n.s 74.0 Weakly correlated
40 L1MA4A 2 n.s 87.0 Weakly correlated
41 AluSc 2 n.s 74.0 Weakly correlated
42 HAL1 2 n.s 99.0 Highly correlated
43 AluSq2 2 n.s 74.0 Weakly correlated
44 L1MC1 2 n.s 99.0 Highly correlated
45 AluJr4 1 n.s 74.0 Weakly correlated
46 AluJb 1 n.s 74.0 Weakly correlated
47 MIR1_Amn 1 * 319.0 Weakly correlated
48 LTR37A 1 ** 99.0 Highly correlated
49 LTR18C 1 **** 43.0 Weakly correlated
50 AluSq 1 n.s 74.0 Weakly correlated
51 AluSx3 1 n.s 74.0 Weakly correlated
52 L2b 1 n.s 99.0 Highly correlated
53 AluYh3 1 ** 15.2 Weakly correlated
54 L2 1 n.s 99.0 Highly correlated
55 L1PREC2 1 n.s 43.0 Weakly correlated
56 L1PB4 1 n.s 99.0 Highly correlated
57 MIRb 1 n.s 99.0 Highly correlated
58 L1PA2 1 n.s 15.2 Weakly correlated
59 MLT1A 1 n.s 99.0 Highly correlated
60 MLT1A1 1 n.s 87.0 Weakly correlated
61 MLT1B 1 n.s 99.0 Highly correlated
62 MLT1E2 1 * 99.0 Highly correlated
63 MLT1F1 1 * 99.0 Highly correlated
64 MLT1H-int 1 ** 99.0 Highly correlated
65 MLT1I 1 n.s 99.0 Highly correlated
66 MLT1J2 1 * 99.0 Highly correlated
67 MLT1L 1 n.s 99.0 Highly correlated
68 MLT2B1 1 * 99.0 Highly correlated
69 MLT2B4 1 * 99.0 Highly correlated
70 MLT2F 1 ** 99.0 Highly correlated
71 SVA_A 1 ** 19.6 Weakly correlated
72 L1MA2 1 n.s 74.0 Weakly correlated
73 L1MC4 1 n.s 99.0 Highly correlated
74 L1MC4a 1 n.s 99.0 Highly correlated
75 L1MC5 1 n.s 99.0 Highly correlated
76 L1MC5a 1 n.s 99.0 Highly correlated
77 L1MC2 1 n.s 99.0 Highly correlated
78 L1MCb 1 * 99.0 Highly correlated
79 L1MCc 1 * 99.0 Highly correlated
80 L1MD3 1 n.s 99.0 Highly correlated
81 L1MB8 1 n.s 99.0 Highly correlated
82 L1MB5 1 n.s 99.0 Highly correlated
83 L1ME2z 1 n.s 99.0 Highly correlated
84 L1MA7 1 n.s 87.0 Weakly correlated
85 L1MA3 1 n.s 74.0 Weakly correlated
86 L1ME3C 1 * 99.0 Highly correlated
87 L1PB 1 * 74.0 Weakly correlated
88 L1MA1 1 n.s 74.0 Weakly correlated
89 L1M7 1 * 99.0 Highly correlated
90 L1M5 1 n.s 99.0 Highly correlated
91 L1M4c 1 n.s 99.0 Highly correlated
92 L1M4b 1 n.s 99.0 Highly correlated
93 L1M3e 1 ** 99.0 Highly correlated
94 L1M3d 1 ** 99.0 Highly correlated
95 L1M2c 1 ** 87.0 Weakly correlated
96 FLAM_A 1 * 74.0 Weakly correlated
97 L1P1 1 n.s 19.6 Weakly correlated
98 L1PA16 1 n.s 74.0 Weakly correlated
99 L1MC3 1 n.s 99.0 Highly correlated
100 AluYj4 1 * 0.0 Weakly correlated
Motif in Repeats The motif of KZFPs identified by the MEME-ChIP is present in repeats sequences. :
# Repeats name Record number Significance Emergence time(Mya) Time correlation with KZFP
1 L1MEd 159 **** 99.0 Highly correlated
2 L1MEg 75 **** 99.0 Highly correlated
3 L1MEi 16 **** 99.0 Highly correlated
4 L1ME3B 7 **** 99.0 Highly correlated
5 L1ME3A 7 **** 99.0 Highly correlated
6 L1MCa 7 **** 99.0 Highly correlated
7 L1ME4a 5 ** 99.0 Highly correlated
8 L1M1 4 * 74.0 Weakly correlated
9 L1MB7 4 n.s 99.0 Highly correlated
10 L1ME1 3 n.s 99.0 Highly correlated
11 L1MEh 3 **** 99.0 Highly correlated
12 L1ME3F 3 *** 99.0 Highly correlated
13 L1ME3E 3 *** 99.0 Highly correlated
14 L1ME3Cz 3 ** 99.0 Highly correlated
15 L1ME3 3 ** 99.0 Highly correlated
16 L1M2 3 * 99.0 Highly correlated
17 L1M4 3 n.s 99.0 Highly correlated
18 L2a 2 n.s 99.0 Highly correlated
19 L1ME3D 2 ** 99.0 Highly correlated
20 L1MC1 2 n.s 99.0 Highly correlated
21 L1MA4A 2 n.s 87.0 Weakly correlated
22 L1MDa 2 n.s 99.0 Highly correlated
23 L1MA1 1 n.s 74.0 Weakly correlated
24 L1MA3 1 n.s 74.0 Weakly correlated
25 L1ME3G 1 n.s 99.0 Highly correlated
26 L1M4c 1 n.s 99.0 Highly correlated
27 L1MEc 1 n.s 99.0 Highly correlated
28 L1M3e 1 ** 99.0 Highly correlated
29 L1M2c 1 ** 87.0 Weakly correlated
30 L1PA16 1 n.s 74.0 Weakly correlated
31 L1PA2 1 n.s 15.2 Weakly correlated
32 L1PB4 1 n.s 99.0 Highly correlated
33 L1PREC2 1 n.s 43.0 Weakly correlated
34 MLT1E2 1 * 99.0 Highly correlated
35 L1MA2 1 n.s 74.0 Weakly correlated
36 L1MC2 1 n.s 99.0 Highly correlated
37 L1ME3C 1 * 99.0 Highly correlated
38 L1MA7 1 n.s 87.0 Weakly correlated
39 L1MB8 1 n.s 99.0 Highly correlated
40 L1ME2z 1 n.s 99.0 Highly correlated
41 L1ME2 1 n.s 99.0 Highly correlated
42 AluJr 1 n.s 74.0 Weakly correlated
43 L1MD3 1 n.s 99.0 Highly correlated
44 L1MCc 1 * 99.0 Highly correlated
45 L1MCb 1 * 99.0 Highly correlated
46 L1MC5a 1 n.s 99.0 Highly correlated
47 L1MC4a 1 n.s 99.0 Highly correlated
48 L1MC3 1 n.s 99.0 Highly correlated
Motif in Repeats Consensus The motif of KZFPs identified by MEME-ChIP analysis can be utilized to locate the corresponding region within the consensus sequences of repeats. :
# Repeats name Emergence time(Mya) Time correlation with KZFP